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Smoking Cessation clinical trials

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NCT ID: NCT06268002 Completed - Smoking Cessation Clinical Trials

Effect of Vernonia Cinerea Lozenges as a Smoking Cessation Aid in Patients With Non-communicable Diseases

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Vernonia cinerea is an herbal which has been recorded in many Thai herbal formulation and Thai traditional medicine has used this herbal for treating various diseases included hypertension, asthma, fever, hepatitis, kidney stone and smoking cessation. Now aday there are more interest for using Vernonia cinerea as a medication to aid smoker to quit smoking because it is cheaper than other current therapeutic medications. The objective of this study is to evaluate efficacy and safety of Vernonia cinerea lozenge for smoking cessation when compared to placebo.

NCT ID: NCT06145685 Completed - Smoking Cessation Clinical Trials

Effect of Smoking Cessation on Salivary IL-1β and PGE-2 Levels Following Non-Surgical Periodontal Therapy

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effect of smoking cessation on inflammatory markers following non-surgical treatment of periodontal disease. This is to assess the period of smoking abstinence needed before any periodontal surgery in order to reverse the negative effects of the reported increased levels of inflammatory markers (IL-1β and PGE2 in this study) associated with smoking on the healing and the periodontium.

NCT ID: NCT06091826 Completed - Smoking Cessation Clinical Trials

Study Assessing Efficacy and Safety of NFL-101 on Reduction of Reinforcing Properties of Cigarettes (PRECESTO)

PRECESTO
Start date: February 21, 2023
Phase: Phase 2
Study type: Interventional

PRECESTO is a randomized, double-blind, cross-over trial on 34 smokers who do not want to stop smoking and get high satisfaction from smoking. The primary objective is to assess efficacy of NFL-101 in reducing the positive reinforcing properties of cigarettes compared to placebo measured by the modified Cigarette Evaluation Questionnaire (mCEQ) "Smoking Satisfaction" (items 1, 2, and 12) subscale.

NCT ID: NCT06003439 Completed - Smoking Cessation Clinical Trials

Vaping Prevention and Vaping in Youth (Vapechat)

Vapechat
Start date: April 4, 2024
Phase: N/A
Study type: Interventional

Many youth are addicted to nicotine due to increased nicotine vaping (e.g., e-cigarettes). Unfortunately, there are no effective interventions to help teens quit vaping. In addition, existing vaping prevention programs have limited effectiveness because teens have reported that existing available interventions are out of touch with teen's culture and are not appealing to the intended audience. Therefore, to be effective, a vaping intervention must be acceptable, appealing, and engaging to teens, and most importantly, it should be designed to be channeled into an existing infrastructure such as the school setting. The investigators' research group has designed a vaping prevention and cessation intervention that is implemented as a VR game for high school teens. The overall objective of this research is to assess the acceptability, feasibility, and preliminary efficacy of the VR experience among high school students in two high schools in Boston.

NCT ID: NCT05981768 Completed - Smoking Cessation Clinical Trials

Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers

Start date: August 8, 2023
Phase: Phase 1
Study type: Interventional

To assess the effect of food on the bioavailability of 3 mg cytisinicline following single-dose administration, and to evaluate the PK profile of 3 mg cytisinicline TID following multiple days of administration during Days 5-8.

NCT ID: NCT05953987 Completed - Smoking Cessation Clinical Trials

Effects of Aerobic Combined With Diaphragmatic Breathing Exercise in Smokers

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

This study aimed to evaluate the effectiveness of aerobic exercise combined with diaphragmatic breathing exercise on pulmonary function and smoking cessation among smokers.

NCT ID: NCT05905666 Completed - Smoking Cessation Clinical Trials

Health Education and Counseling in Smoking Cessation Behavior, Smoking Decisional Balance, and Self-efficacy

Start date: December 29, 2020
Phase: N/A
Study type: Interventional

Most male smokers with coronary heart disease resume smoking after hospital discharge. The main reason for failure to quit smoking is lack of motivation. However, few studies have used individual health education models to explore the effectiveness of smoking cessation according to the stage of change in smoking cessation behavior of patients. The purpose of this study was to examine the effectiveness of health education and counseling on the stages of change, smoking decisional balance, and self-efficacy of smoking cessation in smokers with no intention of quitting.

NCT ID: NCT05873738 Completed - Smoking Cessation Clinical Trials

Smoking Cessation in a Cohort HIV+ Rio de Janeiro, Brazil.

Start date: December 10, 2019
Phase:
Study type: Observational

The study was carried out within a large, urban prospective cohort of PLHIV at the Instituto Nacional de Infectologia Evandro Chagas (INI). Located in Rio de Janeiro, Brazil, INI is a national public referral center for PLWHA receiving primary care since 1998. From December 2019, adults who had attitudes toward quitting smoking and had no contraindications to study pharmacotherapy were enrolled by active site searching

NCT ID: NCT05855343 Completed - Smoking Cessation Clinical Trials

Exploratory Study of Switching From Combustible Cigarettes to the BIDI E-cigarette

Start date: February 14, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to shed light on the importance of nicotine pharmacokinetics in switching to a reduced-harm product by fully matching the nicotine pharmacokinetics of smokers' usual brands of cigarettes. The primary objective is to ascertain the degree of smoking reduction when smokers attempt to switch to an e-cigarette that matches peak nicotine concentrations of a cigarette.

NCT ID: NCT05819086 Completed - Smoking Cessation Clinical Trials

Message Testing in Aging African American Smokers

MCAAAS-2
Start date: March 13, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to examine different messages to motivate smokers who self-identify as an African American current smoker, between the ages of 50-80 years old to quit smoking. Participants will be asked to complete a survey and look at two messages.