Smokers Clinical Trial
Official title:
Evaluation of Efficacy and Safety of Nicotine-Qbeta (NicQb) Vaccine Versus Placebo in Healthy Smokers
The purpose of this study is to help smokers quitting by vaccinating them with CYT002-NicQb. Upon vaccination, the smoker will generate antibodies directed against free nicotine. The antibodies will bind nicotine and prevent its passage into the brain. The successfully vaccinated smoker will have no reward effect after smoking, thus braking the vicious circle of nicotine addiction.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT06123598 -
Effects of Mental Practice and Therapeutic Exercise in Mild Smokers
|
N/A | |
Active, not recruiting |
NCT06108323 -
Immediate Effects of Mental Practice and Therapeutic Exercise in Mild Smokers
|
N/A | |
Completed |
NCT01213706 -
Effect of Whole Body Periodic Acceleration on Airway Endothelial Function
|
N/A | |
Completed |
NCT00781599 -
Improving Medication Compliance and Smoking Cessation Treatment Outcomes for African American Smokers
|
N/A | |
Completed |
NCT02354677 -
Repair, Remodeling and Regeneration of the Bronchial Epithelium of COPD Patients
|
N/A | |
Completed |
NCT00918073 -
Evaluation of Cardiovascular Effects of Smoking Cessation in HIV Patients
|
N/A | |
Not yet recruiting |
NCT03299634 -
Oral Mucosal Lesions Among Smokers in an Egyptian Population Study.
|
N/A | |
Completed |
NCT03299595 -
Oral Mucosal Lesions Among Smokers in an Egyptian Population.
|
||
Completed |
NCT00483015 -
Differences in the Presentation Outcome and Response to Treatment Between Never- Smokers and Smokers With NSCLC
|
N/A | |
Completed |
NCT01182129 -
4 mg Nicotine Polacrilex Gum and Swedish Portion Snus
|
Phase 1/Phase 2 | |
Terminated |
NCT01345383 -
Impact of Current Smoking in the Tolerance of Bronchoscopy
|
N/A | |
Completed |
NCT01734330 -
Cognitive Behaviour Therapy and Nicotine Replacement to Increase Tobacco Cessation
|
N/A | |
Completed |
NCT01362101 -
Effect of Behavioral Training on Physiological Responses to Smoking Cues, Affect and Cortisol
|
Phase 4 | |
Completed |
NCT00341640 -
Metabolism of Nicotine and Cotinine in Pregnant African-American Women
|
Phase 1 | |
Completed |
NCT03086707 -
Prefatory Study to Explore Changes in Nasal Mucociliary Clearance and to Standardize Nasal Scraping Procedure
|
N/A | |
Completed |
NCT01566968 -
Novel Endpoints in Cough Challenge Testing
|
N/A | |
Active, not recruiting |
NCT05758272 -
Evaluation of a Workplace Smoking Cessation Program in Hong Kong (Phase VI)
|
N/A | |
Completed |
NCT03608293 -
Smoker Extracellular Vesicles Influence on Human Bronchial Epithelial Cells
|
N/A | |
Not yet recruiting |
NCT04252781 -
Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC)
|
N/A | |
Completed |
NCT04099225 -
Multiple Breath Washout (MBW) Using Sulfur Hexafluoride Reference Values and Influence of Anthropometric Parameters
|