PTSD Clinical Trial
Official title:
Efficacy of a Brief Nightmare Treatment for Veterans
The purpose of this study is to find out what effects Exposure, Rescripting, and Relaxation Therapy (ERRT) has on nightmares and associated problems in veterans.
The purpose of the proposed pilot study is to extend previous findings regarding the impact
of a brief cognitive behavioral treatment for chronic nightmares by examining the emotional,
cognitive, behavioral, and health-related changes following treatment. Experiencing a
traumatic event may initiate or exacerbate the occurrence of nightmares. Indeed, sleep
disturbance, including nightmares, is considered a hallmark of posttraumatic stress disorder
(PTSD). Nightmares have been related to a variety of factors including stress, medications,
trauma, and substance use. Among veterans, especially combat veterans or those reporting
sexual assaults, symptoms of traumatic stress and nightmares are extremely common. Few
studies have investigated the efficacy of nightmare treatment in a veteran population, and
the impact of nightmare treatment on suicidal ideation has never been assessed.
Imagery Rehearsal Treatment (IRT) has received increased attention in the past decade for use
with chronic nightmares. Studies suggest that the treatment is promising for the reduction of
frequency and intensity of chronic nightmares in trauma exposed persons and may have a
generalized impact on symptoms of posttraumatic stress disorder and depression and
quality/quantity of sleep, although there is mixed evidence for sleep improvement among
veterans. The principal investigator has completed two randomized controlled trials of a
modified version of IRT, Exposure, Rescripting, and Relaxation Treatment (ERRT) and is
currently conducting a third randomized controlled trial (Davis, 2008; Davis & Wright, 2007).
The current randomized controlled trial is comparing ERRT to an active treatment
(relaxation). Results demonstrated positive treatment response. Although these trials have
included some veteran participants, veterans have not been studied as a group using this
protocol. The purpose of this prospective study is to conduct a pre- and post-treatment
comparison of suicidal ideation and posttraumatic, depressive, and health symptoms in a
single group of veterans.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT03962504 -
Written Exposure Therapy Versus Prolonged Exposure: a Non-inferiority Trial
|
N/A | |
Completed |
NCT01995123 -
Behavioral Activation for Smoking Cessation in PTSD
|
N/A | |
Not yet recruiting |
NCT06278922 -
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
|
N/A | |
Completed |
NCT04597450 -
Lu AG06466 in Participants With Post Traumatic Stress Disorder (PTSD)
|
Phase 1 | |
Completed |
NCT03593772 -
Mission Reconnect- Delivering a Mobile and Web Based Self Directed Complementary And Integrative Health Program to Veterans and Their Partners to Manage Pain and PTSD
|
N/A | |
Completed |
NCT03429166 -
Connecting Women to Care: Home-based Psychotherapy for Women With MST Living in Rural Areas
|
N/A | |
Recruiting |
NCT04317820 -
Deep Brain Reorienting in Post-traumatic Stress Disorder
|
N/A | |
Active, not recruiting |
NCT04588883 -
Strengthening Families Living With HIV in Kenya
|
N/A | |
Completed |
NCT03504722 -
Evaluating the Feasibility of RESCUE: An Adjunctive HAI-Based Intervention for Veterans With PTSD
|
N/A | |
Completed |
NCT04305353 -
Intensive Care Unit (ICU) Diary Project
|
N/A | |
Completed |
NCT03113890 -
McLean and Genomind Prospective Study
|
N/A | |
Withdrawn |
NCT05173831 -
Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in Veterans
|
Phase 2 | |
Withdrawn |
NCT03924297 -
Chilipad for Sleep and Symptoms of PTSD
|
N/A | |
Not yet recruiting |
NCT04056767 -
Changes in Digital Phenotype During PE Therapy
|
||
Completed |
NCT03158558 -
Intensive Weekend Retreat Multi-Couple Group Therapy for PTSD
|
N/A | |
Withdrawn |
NCT03216356 -
Effect of D-cycloserine on a Short Imagery Rescripting Intervention for Subclinical PTSD
|
Phase 2/Phase 3 | |
Completed |
NCT03343028 -
Biomarker Establishment for Superior Treatment of PTSD
|
||
Completed |
NCT02370173 -
A Non-Pharmacological Method for Enhancing Sleep in PTSD
|
N/A | |
Completed |
NCT01911585 -
Efficacy of 60-minute Versus 90-minute Sessions in Treating PTSD Using Prolonged Exposure
|
N/A | |
Completed |
NCT01955538 -
The Effect of BAT Versus Mixed Physical Activity as add-on Treatment for Traumatised Refugees.
|
Phase 3 |