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Sleep Apnea, Obstructive clinical trials

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NCT ID: NCT05987618 Completed - Clinical trials for Sleep Apnea, Obstructive

Oral Appliances With and Without Elastic Bands to Treat Obstructive Sleep Apnea: A Randomized Crossover Trial

Start date: April 15, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized crossover trial is to investigate the effect of elastic bands attached to oral appliances to minimize mouth opening during sleep in obstructive sleep apnea (OSA) patients. The main questions it aims to answer are: - Are the success rates (>50% reduction of AHI) of oral appliances with elastic bands superior to oral appliances treatment without elastic bands in treatment of moderate and severe OSA? - Are there predictors that can identify patients that will benefit from use of elastic bands in oral appliance treatment of OSA? - Are there predictors that can identify patients that are classified as non-responders to oral appliance treatment in general, both with and without elastic bands? Participants will be treated with oral appliances with and without elastic bands for 3 weeks, in randomized order. At the end of each 3-week period, the effect of the treatment will be investigated with sleep registrations and questionnaires. After the completion of both 3-week periodes, patients will continue using their preferred treatment modality (with or without elastic bands) and the oral appliance will be titrated if suboptimal treatment effect.

NCT ID: NCT05967754 Completed - Clinical trials for Obstructive Sleep Apnea

Correlation Between Serum Uric Acid and Pulmonary Hypertension in Obstructive Sleep Apnea Syndrome

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

This study aimed to correlate serum uric acid levels and PAH in OSAHS patients.

NCT ID: NCT05934916 Completed - Covid19 Clinical Trials

Early Application of Continuous Positive Airway Pressure in Coronavirus Patients at Risk of Obstructive Sleep Apnea

Start date: August 1, 2021
Phase: N/A
Study type: Interventional

This was an experimental clinical trial, Aim: To evaluate the role of early use of Continuous Positive Airway Pressure (CPAP) in management of moderate to severe Coronavirus disease 2019 patients at risk of Obstructive Sleep Apnea, enrolled patients are randomized into two equal groups;Non- CPAP group and CPAP group. Non-CPAP group will receive medical treatment plus oxygen therapy according to recommendation of protocol of the Egyptian Ministry of Health 2020 and CPAP group as in Non-CPAP group plus using CPAP.

NCT ID: NCT05894733 Completed - Sleep Disorder Clinical Trials

The Effects of Frequent Follow up on Compliance in Patients Receiving PAP Therapy Due to OSA (Pap: Positive Airway Pressure, OSA: Obstructive Sleep Apnea )

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The investigators planned to investigate the effect of close monitoring on compliance and the factors affecting compliance among patients receiving PAP treatment due to OSA.This study was a single-center, prospective, randomized, controlled study approved by the hospital's ethics committee.One hundred twenty-eight patients were randomized as group one or two as group 1 is the study and group 2 is the control group. The first group was called by phone on the 15th day to ask if there were any complaints or problems with the device. Sequentially, they were called for controls at the end of the first, third, and sixth months. The second group was accepted as the control group, following our clinic's standard procedure in the first and sixth months. The patients who came to the control were asked if there were any problems with the device and any difficulties in use, and they were again informed about the devices and masks.

NCT ID: NCT05881824 Completed - Clinical trials for Obstructive Sleep Apnea

PAP Adherence After Diet/Lifestyle Intervention in OSA Patients

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to explore the role of diet/lifestyle intervention on Positive airway pressure (PAP) treatment adherence in patients with obstructive sleep apnea (OSA).Specifically, we evaluated the effects of a combination of PAP and weight-loss Mediterranean diet intervention on improving PAP adherence, Body mass index (ΒΜΙ), daytime symptoms, mainly sleepiness and arterial blood pressure measurements over the effect of standard care alone.

NCT ID: NCT05881512 Completed - Clinical trials for Obstructive Sleep Apnea

Early Feasibility Study of Transcutaneous Upper Airway Stimulation in Obstructive Sleep Apnea

Start date: September 12, 2022
Phase: N/A
Study type: Interventional

Early feasibility study to estimate the functionality of a novel intervention based on non-invasive transcutaneous electrical stimulation of the hypoglossal nerve to reduce the Apnea Hypopnea Index (AHI).

NCT ID: NCT05818540 Completed - Clinical trials for Obstructive Sleep Apnea

Sleep Apnea Study in Adults Using DreamPort-Eclipse and a Traditional Nasal Mask

Start date: April 17, 2023
Phase: N/A
Study type: Interventional

The Randomized Controlled Trial of Bleep DreamPort-Eclipse Study is a two-arm, randomized, prospective, non-blinded study to assess the effectiveness of the novel CPAP human interface design to improve leak, AHI, and pressure compared to a traditional nasal mask.

NCT ID: NCT05817123 Completed - Clinical trials for Obstructive Sleep Apnea

Validation of the Mutuality Scale in Patients With OSA and Their Partners

VAMOS
Start date: May 10, 2021
Phase:
Study type: Observational

Main objective of this study is to assess the psychometric characteristics of the Mutuality Scale both in patients with Obstructive Sleep Apnea Syndrome (OSAS) and in their partners-The association between the mutuality score in OSAS patients and their adherence to the use of Continuous Positive Airway Pressure (CPAP) therapy will also be investigated. The results of the study may allow a validation of the Mutuality Score as an instrument for measuring mutuality between OSAS patients and their partners.

NCT ID: NCT05793684 Completed - Clinical trials for Obstructive Sleep Apnea

AD816 Crossover Study

VicTor
Start date: April 28, 2023
Phase: Phase 2
Study type: Interventional

The VicTor Study is a randomized, double blind, placebo-controlled, 3-period, multiple-dose crossover study in participants with OSA.

NCT ID: NCT05734742 Completed - OSA Clinical Trials

Attitudes Toward Obstructive Sleep Apnea-Related Cause of Road Traffic Accidents in Thailand Through Well Prepared Educational Video

AOSARTA
Start date: December 31, 2022
Phase: N/A
Study type: Interventional

The goal of this descriptive, cross-sectional survey design is to determine the effect of public awareness video on the basic knowledge regarding sleep apnea syndrome or glaucoma and traffic accidents in normal population The main questions it aims to answer are: - To assess the attitudes toward the health-related cause of traffic accidents, mainly focused on obstructive sleep apnea and glaucoma among Thai people who viewed the local language translated versions of the public awareness video. - To assess the feedbacks of the public awareness video. Participants will be ask to complete a set of questionnaires containing 3 parts - pre-test part - educational video part - post-test part