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Sleep Apnea, Obstructive clinical trials

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NCT ID: NCT00936494 Terminated - Clinical trials for Obstructive Sleep Apnea

Inferior Turbinate Reduction in Pediatric Population Failing Surgery for Sleep Disordered Breathing

Start date: June 2009
Phase: N/A
Study type: Interventional

This study will examine whether treatment of inferior turbinates in patients with continued symptoms of obstructive sleep apnea, sleep related breathing disorder, snoring, disturbed sleeping, open mouth breathing, and upper airway resistance syndrome after tonsillectomy and adenoidectomy will improve these symptoms and should be included in the treatment paradigm for treatment of sleep related breathing disorders in infants, children, and adolescents.

NCT ID: NCT00790166 Terminated - Clinical trials for Obstructive Sleep Apnea

Effects of Humidity (During CPAP Treatment) on Mucociliary Clearance in Patients With Obstructive Sleep Apnea

CIA-6
Start date: October 2008
Phase: N/A
Study type: Interventional

That the level of humidification delivered to patients during CPAP treatment will alter the subjects mucociliary clearance rate and related mucus properties.

NCT ID: NCT00730041 Terminated - Clinical trials for Obstructive Sleep Apnea (OSA)

Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea

Pillar-CPAP
Start date: November 2007
Phase: Phase 4
Study type: Interventional

The study will be done for the following purposes: - to see if Pillar implants in combination with CPAP therapy can help people with their OSA by decreasing the CPAP pressures - to find out if receiving Pillar implants will increase CPAP use

NCT ID: NCT00727454 Terminated - Clinical trials for Obstructive Sleep Apnea

Effects of Continuous Positive Airway Pressure (CPAP) in Heart Remodeling by Magnetic Resonance Imaging (MRI)

OSA-MRI
Start date: July 2007
Phase: Phase 4
Study type: Interventional

Obstructive sleep apnea (OSA) is independently associated with important heart remodeling that further contributes to overt heart failure. Recent evidences using echocardiogram suggested that continuous positive airway pressure (CPAP) has beneficial effects mainly on left ventricle parameters. However, the evidences regarding the right ventricle are scanty. In addition, no previous studies evaluated morphological and functional characteristics in OSA by magnetic resonance imaging (MRI) as well as the impact of CPAP.

NCT ID: NCT00669695 Terminated - Clinical trials for Obstructive Sleep Apnea Syndrome

Systemic Inflammation and Obstructive Sleep Apnea Syndrome: Effect of Atorvastatin

StatinflaSAS
Start date: May 2008
Phase: Phase 2
Study type: Interventional

The aim of this clinical trial is to evaluate the effect of Atorvastatin on the endothelial function improvement during the obstructive sleep apnea syndrome (OSAS) after 3 months of treatment, by a double-blind, randomized, placebo-controlled, multi-center study. An interim analysis will be performed when 25 patients per group will be included.

NCT ID: NCT00646971 Terminated - Oxidative Stress Clinical Trials

Oxidative Stress and Endothelial Dysfunction in Obstructive Sleep Apnea

SOREVAS
Start date: January 2008
Phase: N/A
Study type: Interventional

Patients with sleep apnea syndrome have repeated apneic events that induce periodic hypoxia-reoxygenation, drawing away an overproduction of oxidants. This exaggerated generation of oxidants is associated with a dysfunction of the vascular endothelium that evolves, in its turn, towards cardiovascular diseases such as systemic hypertension, stroke, and myocardial infarction. The major aim of our study is to examine the effect of CPAP treatment on biochemical (markers of oxidative stress) and functional (endothelium-dependent vascular relaxation reactivity) abnormalities at 1 and 4 weeks of treatment.

NCT ID: NCT00620659 Terminated - Clinical trials for Sleep Apnea, Obstructive

Treatment of Refractory Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSA/HS) Using Nasal Continuous Positive Airway Pressure (nCPAP) Therapy (0249-015)

Start date: February 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of MK0249 in treating refractory excessive daytime sleepiness (EDS) in patients with Obstructive Sleep Apnea/Hypopnea Syndrome (OSA/HS) using nasal continuous positive airway pressure (nCPAP) therapy.

NCT ID: NCT00588848 Terminated - Clinical trials for Obstructive Sleep Apnea

CPAP vs AutoCPAP for Treatment of Obstructive Sleep Apnea (OSA) in the Postoperative Setting

Start date: January 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if an Autoadjusting CPAP machine is better than the regular CPAP machine in treatment of Obstructive Sleep Apnea in the postoperative setting.

NCT ID: NCT00515580 Terminated - Clinical trials for Obstructive Sleep Apnea

Minimally Invasive Tongue Suture For Obstructive Sleep Apnea

Start date: August 2007
Phase: N/A
Study type: Interventional

This is a pilot study to determine the usefulness of a newly developed, minimally invasive tongue suture procedure for people with obstructive sleep apnea.

NCT ID: NCT00456339 Terminated - Clinical trials for Obstructive Sleep Apnea Syndrome

Systemic Steroids Plus Antibiotics in Sleep Apnea Syndrome in Children

Start date: July 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate the effect of treatment with a steroid and antibiotic on the size of the tonsils and symptoms of children with OSAS.