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Skin Wound clinical trials

View clinical trials related to Skin Wound.

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NCT ID: NCT05517902 Active, not recruiting - Burns Clinical Trials

StrataGraft Safety, Tolerability and Efficacy in Pediatric Subjects

StrataSTEPS
Start date: April 28, 2023
Phase: Phase 3
Study type: Interventional

Autografting is a surgical procedure to transplant healthy skin (donor skin) from another part of the participant's own body (donor site) to the burned part. Autografting is the usual treatment for DPT burns. It works to close the wound, but can cause other problems: - Donor sites are painful, can become infected or scarred, or can even become full thickness (FT) wounds themselves - Treatment problems can require more grafting - Additional surgery increases the risk of medical problems caused by the treatment Stratatech is trying to find a safe and effective alternative to autografting to promote the healing of severe burns. The purpose of this study is to evaluate whether StrataGraft treatment eliminates or reduces the need for autografting and promotes wound closure in a pediatric population with thermal burns that contain intact dermal elements and for which autografting is clinically indicated (DPT burns). Participants will be enrolled into one of two age-based cohorts: 2 to < 12 years and 12 to ≤ 17 years to receive a single application of StrataGraft, in up to 3 non-contiguous DPT burn areas located on the same extremity or plane of the torso. The study will last for approximately 2.5 years.

NCT ID: NCT03649308 Active, not recruiting - Wound Heal Clinical Trials

Negative Pressure Wound Therapy Compared to Traditional Care After Skin Grafting

TRUTH
Start date: September 19, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to compare negative pressure wound therapy to traditional care after split-thickness skin grafting in patients aged over 18.

NCT ID: NCT03394612 Active, not recruiting - Skin Wound Clinical Trials

Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Full-Thickness Skin Defects in Adults and Children

Start date: February 14, 2018
Phase: Phase 2
Study type: Interventional

This phase II trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in adults and children with full-thickness Skin defects.