Nutritional Study of Fish Oil in Skin Quality in Healthy Women

Skin Health Clinical Trial

— OPTIHUD  

Official title:

A Randomised, Two-armed, Double-blinded Nutritional Study of Fish Oil on Skin Quality in Healthy Women

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05128240
• Other study ID #: P237921
• Status: Recruiting
• Phase: N/A
• Start date: August 23, 2021
• Est. completion date: March 1, 2022

Study information

• Verified date: November 2021
• Source: Epax Norway AS
• Contact: Derek Tobin, PhD
• Email: derek.tobin[@]pelagia.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The skin acts as a barrier against the external environment and prevents water loss from the body. Aging is a natural process leading to changes in the skin and fish oil has been shown to prevent inflammation, hyperpigmentation and UV-damage. This pilot study will determine skin characteristics after intervention with north atlantic fish oil.

Description:

Women will be recruited to a placebo or fish oil group and be examined at pre- and post for skin quality parameters such as wrinkles, fine lines and trans-epithelial water loss.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30
• Est. completion date: March 1, 2022
• Est. primary completion date: December 20, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 30 Years to 65 Years

Eligibility

Inclusion Criteria:

Healthy women in the age of 30-65

Able to follow the following dietary restriction for 4 months (4 weeks wash-out, 3 months intervention):

• Do not take omega-3 supplements

• do not take supplements containing vitamin A

• do not take supplements containing collagen

• try to avoid using skin products containing vitamin A

• do not undergo skin treatment

Exclusion Criteria:

Pregnancy or breast feeding known allergy to seafood skin treatment the last 6 months planned skin treatment during the study period

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Related Conditions & MeSH terms

• Skin Health

Intervention

Dietary Supplement:
• Placebo
1g corn oil capsules
• Ceto 10
1g capsules containing oil broad spectrum marine oil from north atlantic fish

Locations

Country	Name	City	State
Norway	Møreforsking AS	Ålesund

Sponsors (2)

Lead Sponsor	Collaborator
Epax Norway AS	Møreforsking AS

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Determine the change in skin quality of healthy women after supplementation with fish oil compared to corn oil	Changes in quantitative analysis of facial inflammation, wrinkles and fine lines and skin texture will be performed using the VISIA Skin Analysis system. Measurements will be made at baseline and at end of supplementation period.	3 months
Secondary	Determine the change in omega-3 index (%EPA and DHA in red blood cells) after daily intake of 4g of north atlantic fish oil compared to placebo	Fatty acid profiles will be measured from blood samples using the Omega-quant test	3 months