Clinical Trials Logo
  1. Home
  2. Skin Health
  3. NCT04183920

To Determine the Activity and Mechanisms of Cranberries to Attenuate Skin Photoaging and Improve Skin Health in Women

Skin Health Clinical Trial

Official title:
To Determine the Activity and Mechanisms of Cranberries to Attenuate Skin Photoaging and Improve Skin Health in Women

Clinical Trial Summary

Previous studies have shown that cranberry phytochemicals scavenge reactive carbonyls. Cranberry polyphenols have been reported to attenuate collagen degradation and inhibit oxidative stress in human cells. We hypothesize that cranberry juice consumption will attenuate skin photoaging and improve skin health in women via alleviate oxidative stress.

Clinical Trial Description

One of the causative factors of skin ageing is cumulative oxidative damages due to aerobic metabolism and UV irradiation. Cumulation of reactive oxygen species (ROS) causes collagen glycation and crosslinking which are direct causes of skin ageing. Previous studies have shown that cranberry phytochemicals scavenge reactive carbonyls. Cranberry polyphenols have been reported to attenuate collagen degradation and inhibit oxidative stress in human cells. It is unknown whether cranberry juice consumption could protect against UV -induced erythema and improve overall skin health. Furthermore, if it does have effect, what will be the mechanism? This human intervention study will be conducted to answer these questions. We hypothesize that cranberry juice consumption will attenuate skin photoaging and improve skin health in women via alleviate oxidative stress. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04183920
Study type Interventional
Source University of Florida
Contact Lindsey Morgan Christman
Phone 352-294-3731
Email lchristman@ufl.edu
Status Recruiting
Phase N/A
Start date February 7, 2020
Completion date February 3, 2026
View Details
See also
  Status Clinical Trial Phase
Completed NCT04544982 - Study to Evaluate the Efficacy of Blue Fenugreek Kale Extract (BFKE) on Skin N/A
Completed NCT03346447 - Effect of Baby Wipe Solutions on Fecal Enzyme-induced Irritation N/A
Completed NCT05861622 - Examining the Efficacy of a Novel Moisturizer Across Eight Weeks N/A
Active, not recruiting NCT04614753 - Dealcoholized Muscadine Wine and Skin Health in Women N/A
Recruiting NCT06148740 - An Investigation of the Effects of a Skin Serum Containing Propolis on Skin Health and Appearance N/A
Active, not recruiting NCT06148753 - An Investigation of the Effects of a Royal Jelly and Bee Venom-Derived Skin Serum on Skin Health and Signs of Aging N/A
Active, not recruiting NCT06148766 - An Investigation of the Effects of a Royal Jelly and Bee Venom-Derived Skin Cream on Skin Health and Signs of Aging N/A
Completed NCT04511052 - Probiotics for Enhanced Tissue Carotenoid Status in Premenopausal Women Phase 1/Phase 2
Recruiting NCT05925712 - Aerofit Post Market Investigation N/A
Completed NCT02525224 - Nutritional Supplement Efficacy on Cellular Protection and Skin Health in Generally Healthy Adults N/A
Completed NCT04144777 - Efficacy of Solarplast for Health and Oxidative Stress N/A
Recruiting NCT04861623 - Effects of 100% Orange Juice on Skin Health in Women N/A
Completed NCT03771807 - Efficacy of a Nutritional Supplement on Skin Health in Generally Healthy Adults N/A
Completed NCT00864188 - The Influence of Probiotics in a Drinkable Yogurt on Skin Health Phase 1
Completed NCT03348917 - The Effect of Skin Cleansers on the Skin Surface Microbiome Phase 4
Withdrawn NCT03641430 - The Effects of Over-the-Counter Products on the Skin N/A
Recruiting NCT05128240 - Nutritional Study of Fish Oil in Skin Quality in Healthy Women N/A
Completed NCT00574574 - Effects of Anthocyanin on Skin Health and Markers of Cardiovascular Disease Risk N/A