Skin Diseases, Infectious Clinical Trial
— ToPICLOfficial title:
Pilot Study: Topical Antibiotics for Prevention of ICU Central Line Infections
Verified date | May 2015 |
Source | Fraser Health |
Contact | n/a |
Is FDA regulated | No |
Health authority | Canada: Ethics Review Committee |
Study type | Interventional |
The purpose of the study is to determine if the overall central venous catheter related infection rate can be reduced by the application of Polysporin Triple Therapy ointment to the insertion site.
Status | Withdrawn |
Enrollment | 0 |
Est. completion date | January 2011 |
Est. primary completion date | January 2011 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - all patients admitted to the ICU requiring a central venous catheter Exclusion Criteria: - previous line infection during same ICU stay - CVC for hemodialysis |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Canada | Royal Columbian Hospital | New Westminster | British Columbia |
Lead Sponsor | Collaborator |
---|---|
Fraser Health |
Canada,
James MT, Conley J, Tonelli M, Manns BJ, MacRae J, Hemmelgarn BR; Alberta Kidney Disease Network. Meta-analysis: antibiotics for prophylaxis against hemodialysis catheter-related infections. Ann Intern Med. 2008 Apr 15;148(8):596-605. — View Citation
Lok CE, Stanley KE, Hux JE, Richardson R, Tobe SW, Conly J. Hemodialysis infection prevention with polysporin ointment. J Am Soc Nephrol. 2003 Jan;14(1):169-79. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Overall number of line related infections (local and blood borne) | 6 months | No | |
Secondary | Length of ICU stay | 7 months | No | |
Secondary | Length of hospital stay | 7 months | No | |
Secondary | Prevalence of methicillin-resistant Staphylococcus Aureus (MRSA) | 12 months | Yes |
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