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Skin Diseases, Bacterial clinical trials

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NCT ID: NCT02991131 Terminated - Clinical trials for Skin Disease, Infectious

Sivextro in Acute Bacterial Skin and Skin Structure Infection (ABSSSI) in Hospitalized Patients. A Global Observational Study

DART
Start date: December 17, 2016
Phase:
Study type: Observational

This open-label, prospective, multi-center, non-interventional, observational, parallel cohort study intended to provide real life data on the treatment duration, effectiveness and safety of tedizolid and linezolid when treating ABSSSI hospitalized patients in a real practice setting.

NCT ID: NCT02979951 Recruiting - Sepsis Clinical Trials

Fosfomycin i.v. for Treatment of Severely Infected Patients

FORTRESS
Start date: December 2016
Phase:
Study type: Observational

The purpose of this European, multicentric, prospective, non-interventional study is to document and evaluate the efficacy and safety of the treatment of severely infected patients with intravenously administered fosfomycin, including patients with osteomyelitis, complicated urinary tract infection, nosocomial lower respiratory tract infection, bacterial meningitis/central nervous system infection, bacteraemia/sepsis, skin and soft tissue infection, endocarditis or other infections, each as far as covered by the respective nationally relevant SmPC.

NCT ID: NCT02961764 Completed - Clinical trials for Acute Bacterial Skin and Skin Structure Infections

Evaluation of a New Critical Pathway for Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI)

Start date: November 29, 2016
Phase: Phase 4
Study type: Interventional

This study will evaluate a new critical pathway (use of guideline-based patient identification criteria and for those who meet these criteria, use of dalbavancin) for the treatment of ABSSSI compared to usual care.

NCT ID: NCT02925416 Completed - Clinical trials for Skin Diseases, Bacterial

Safety of Either a Single or Two Intravenous Doses of Orbactiv in Participants With Acute Bacterial Skin and Skin Structure Infection

Start date: January 24, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study was to evaluate the safety and tolerability of two 1200 milligram (mg) intravenous (IV) infusions of oritavancin when administered one week apart.

NCT ID: NCT02814916 Completed - Clinical trials for Bacterial Infections

Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

Start date: March 31, 2017
Phase: Phase 3
Study type: Interventional

To determine the safety and descriptive efficacy of dalbavancin for the treatment of acute bacterial skin and skin structure infections in children, aged birth to 17 years (inclusive), known or suspected to be caused by susceptible Gram-positive organisms, including methicillin-resistant strains of Staphylococcus aureus.

NCT ID: NCT02570490 Completed - Clinical trials for Acute Bacterial Skin and Skin Structure Infections

Oral Sodium Fusidate (CEM-102) Versus Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Start date: November 2015
Phase: Phase 3
Study type: Interventional

Phase 3, randomized, double-blind, multi-center efficacy and safety study to evaluate an oral CEM-102 loading dose regimen compared to oral linezolid in the treatment of subjects with ABSSSI

NCT ID: NCT02477514 Completed - Clinical trials for Skin Diseases, Bacterial

A Study to Evaluate the Effects of Tedizolid Phosphate on the Pharmacokinetics and Safety of Midazolam and Rosuvastatin (MK-1986-004)

Start date: June 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the effect of steady-state tedizolid phosphate on the single-dose pharmacokinetics of midazolam and rosuvastatin in healthy, adult participants.

NCT ID: NCT02452918 Completed - Clinical trials for Acute Bacterial Skin and Skin Structure Infection

A Study to Evaluate the Safety of a Single Intravenous (IV) Dose of Orbactiv (Oritavancin) in Participants on Chronic Warfarin Therapy Being Treated For Acute Bacterial Skin and Skin Structure Infection (ABSSSI)

Start date: September 29, 2015
Phase: Phase 4
Study type: Interventional

This was a Phase 4, multicenter, open-label safety study of a single 1200 milligrams (mg) IV infusion of oritavancin in adult participants on chronic warfarin with acute bacterial skin and skin structure infection (ABSSSI) suspected or proven to be caused by Gram-positive pathogens. An additional group of participants with ABSSSI, who were not on concomitant warfarin therapy, were also enrolled to obtain additional information following a single dose of oritavancin administration.

NCT ID: NCT02276482 Completed - Clinical trials for Skin Diseases, Infectious

Study of Tedizolid Phosphate in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-012)

Start date: March 25, 2015
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare the safety of intravenous (IV) and/or oral 6-day 200 mg tedizolid phosphate with 10-day comparator in participants 12 to <18 years with cSSTI.

NCT ID: NCT02269319 Completed - Clinical trials for Bacterial Infections

MRX-I Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infection

ABSSSI
Start date: February 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether MRX-I is as safe and effective as Linezolid in the treatment of adult patients with acute bacterial skin and skin structure infections