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Skin Basal Cell Carcinoma clinical trials

View clinical trials related to Skin Basal Cell Carcinoma.

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NCT ID: NCT03180528 Completed - Clinical trials for Skin Basal Cell Carcinoma

Topical Remetinostat in Treating Patient With Cutaneous Basal Cell Cancer

Start date: July 7, 2018
Phase: Phase 2
Study type: Interventional

This phase 2 trial studies how well remetinostat works in treating patients with skin basal cell cancer. Remetinostat may slow the growth of basal cell cancer cells.

NCT ID: NCT02978625 Active, not recruiting - Clinical trials for Merkel Cell Carcinoma

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

Start date: September 27, 2017
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well talimogene laherparepvec and nivolumab work in treating patients with lymphomas that do not responded to treatment (refractory) or non-melanoma skin cancers that have spread to other places in the body (advanced) or do not responded to treatment. Biological therapies, such as talimogene laherparepvec, use substances made from living organisms that may stimulate or suppress the immune system in different ways and stop tumor cells from growing. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving talimogene laherparepvec and nivolumab may work better compared to usual treatments in treating patients with lymphomas or non-melanoma skin cancers.

NCT ID: NCT02735356 Completed - Clinical trials for Skin Basal Cell Carcinoma

Topical Itraconazole in Treating Patients With Basal Cell Cancer

Start date: May 5, 2016
Phase: Early Phase 1
Study type: Interventional

This phase 0 trial studies how well itraconazole gel works in treating patients with basal cell cancer. Itraconazole gel may help to treat basal cell tumors in patients.

NCT ID: NCT02699723 Withdrawn - Clinical trials for Skin Basal Cell Carcinoma

Arsenic Trioxide and Itraconazole in Treating Patients With Advanced Basal Cell Cancer

Start date: December 2020
Phase: Early Phase 1
Study type: Interventional

This pilot clinical trial studies how well arsenic trioxide and itraconazole work in treating patients with basal cell cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment. Drugs used in chemotherapy, such as arsenic trioxide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Itraconazole may help treat fungal infections in patients with basal cell cancer. Giving arsenic trioxide with itraconazole may work better in treating basal cell cancer.

NCT ID: NCT02690948 Completed - Clinical trials for Skin Basal Cell Carcinoma

Pembrolizumab With or Without Vismodegib in Treating Metastatic or Unresectable Basal Cell Skin Cancer

Start date: February 1, 2016
Phase: Phase 1/Phase 2
Study type: Interventional

This phase 1-2 trial studies how well pembrolizumab with or without vismodegib works in treating patients with skin basal cell cancer that has spread to other places in the body or cannot be removed by surgery. Monoclonal antibodies, such as pembrolizumab, are checkpoint inhibitors that stimulate immune response. Vismodegib may stop the growth of tumor cells by blocking signals needed for cell growth.

NCT ID: NCT02579551 Completed - Clinical trials for Skin Basal Cell Carcinoma

Effectiveness of Narrow Margins in Patients With Low-Risk Basal Cell Carcinoma Undergoing Surgery

Start date: December 7, 2011
Phase: N/A
Study type: Interventional

This clinical trial studies the effectiveness of narrow margins in patients with low-risk basal cell carcinoma undergoing surgery to remove skin lesions on the face. A margin is the area of normal tissue around a tumor taken out during surgery to make sure all of the cancer is removed. This clinical trial studies tissue samples to determine the least amount of tissue that must be removed to give an acceptable cure rate. This may allow less normal tissue to be removed from patients and may be a less expensive surgery.