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Ro60 Expression in Macrophages in Sjogren's Disease — RoMioSS  

Sjogren's Syndrome Clinical Trial

Official title:
Ro60 Expression in Macrophages in Patients With Primary Sjogren's Syndrome

Clinical Trial Summary

Context: The Ro60 protein associates with YRNAs (or RNYs) to form the RoRNP complex, which regulates RNA surveillance and maturation. It is hypothesized that its impairment by nuclear penetration of the anti-Ro60 autoantibodies, would deregulate the anti-inflammatory response in monocytes/macrophages (Mo/Mp) in patients with Sjögren's disease (SD).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06324968
Study type Interventional
Source Centre Hospitalier Universitaire de Nice
Contact Nihal Nihal MARTIS, MD, MSc
Phone 4 92035444
Email martis.n@chu-nice.fr
Status Recruiting
Phase N/A
Start date February 9, 2024
Completion date February 9, 2026
View Details
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