Voxelotor Neurocognitive Function Study

Status Terminated

Clinical Trial Summary

This is a Phase 3b, randomized, double-blind, placebo-controlled, multicenter study to assess the treatment effect of voxelotor on neurocognitive function as assessed by the National Institute of Health (NIH) Toolbox Cognition Module of executive abilities in pediatric participants (8 to < 18 years) with SCD.

Clinical Trial Description

Eligible participants will receive daily treatment with 1500 mg voxelotor or matching placebo for 12 weeks. During screening and at the end of 12 weeks participants will undergo a series of tests to measure the change in neurocognitive functions. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05228834
Study type	Interventional
Source	Pfizer
Contact
Status	Terminated
Phase	Phase 3
Start date	June 24, 2022
Completion date	September 30, 2022

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