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Clinical Trial Summary

The purpose of this study is to evaluate the efficacy, safety and tolerability of treatment with EDIT-301 in adult subjects with severe sickle cell disease (SCD).


Clinical Trial Description

This is a Phase 1/2 single-arm, open-label, multicenter study evaluating the safety and efficacy of a single unit dose of EDIT-301 for autologous hematopoietic stem cell transplant (HSCT) in subjects with severe SCD. Planned study subjects will be comprised of male and female adult subjects with severe SCD, from 18 to 50 years of age, inclusive. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04853576
Study type Interventional
Source Editas Medicine, Inc.
Contact Editas Medicine's Clinical Trial Team
Phone 617-401-9007
Email [email protected]
Status Recruiting
Phase Phase 1/Phase 2
Start date April 16, 2021
Completion date August 2025

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