Sickle Cell Uric Acid (SCUA) - Cohort Repository

Status Completed

Clinical Trial Summary

The purpose of this research is to study the causes of Sickle Cell kidney disease, as well as to collect and store samples and information about people with Sickle Cell Disease.

Clinical Trial Description

Sickle Cell Disease causes kidney injury over time, but it is not clear why some individuals have very significant chronic kidney disease and why some do not. The purpose of this research is to study whether having high levels of 'uric acid,' which is a naturally occurring molecule in the body that may increase kidney injury and systemic inflammation, accelerates the progression of chronic kidney disease over time. Researchers will measure the number of participants that have high uric acid levels at the beginning of the study, as well as the number of participants that develop new high levels throughout the study. The study will also try to determine what causes the high uric acid levels in some patients but not others. The results of this study could help understand kidney injury and uric acid in sickle cell disease better. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04190888
Study type	Observational [Patient Registry]
Source	Virginia Commonwealth University
Contact
Status	Completed
Phase
Start date	July 1, 2019
Completion date	December 31, 2021

View Details

See also
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