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Evaluation of Non-invasive Endothelial Function in Children Sickle by Vascular Ultrasound

Sickle Cell Disease Clinical Trial

Official title:
Evaluation of Non-invasive Endothelial Function in Children Sickle by Vascular Ultrasound

Clinical Trial Summary

Sickle cell disease (SCD) is an inherited disorder characterized by recurrent painful crises with ischemia resulting from vascular occlusion. Adults with SCD have increased arterial stiffness and reduced flow-mediated dilation (FMD), due to impaired release of substances such as nitric oxide.

The present study assess the vascular properties of carotid and brachial arteries in children with SCD compared with a control group without cardiovascular risk factors.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02829580
Study type Interventional
Source University Hospital, Toulouse
Contact
Status Completed
Phase N/A
Start date September 2008
Completion date February 2013
View Details
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