Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

Sickle Cell Disease Clinical Trial

Official title:

Human Specimen Collection to Support Basic and Clinical Research

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT00047996
• Other study ID #: 030015
• Secondary ID: 03-H-0015
• Status: Recruiting
• Start date: November 4, 2002

Study information

• Verified date: April 12, 2024
• Source: National Institutes of Health Clinical Center (CC)
• Contact: Anna K Conrey, C.R.N.P.
• Phone: (301) 221-3016
• Email: anna.conrey[@]nih.gov
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general conditions under which sample collection will be performed.

Description:

The collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general conditions under which sample collection will be performed.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 2000
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 100 Years

Eligibility

• INCLUSION CRITERIA:

Males or females of age 18 years and older can be included in the study.

EXCLUSION CRITERIA:

Individuals without sickle cell disease or other chronic anemias who wish to donate blood will be excluded if the hemoglobin is less than 10 g/dL for women or less than 12g/dL for men.

Individuals with sickle cell disease or other chronic anemias will be excluded from donating blood samples if the hemoglobin is less than 6 g/dL.

A participant s most recent CBC result, obtained in the past 12 months, will be used to determine eligibility.

There are no exclusion criteria for participants donating saliva or urine.

Related Conditions & MeSH terms

• Anemia, Sickle Cell
• Sickle Cell Disease

Locations

Country	Name	City	State
United States	National Institutes of Health Clinical Center	Bethesda	Maryland
United States	INOVA Fairfax Hosptial	Fairfax	Virginia

Sponsors (1)

Lead Sponsor	Collaborator
National Heart, Lung, and Blood Institute (NHLBI)

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	evaluating the role of nitric oxide, inflammatory mediators, and endothelial function in inflammatory diseases of the vasculature such as sickle cell disease, coronary artery disease, pulmonary vascular or advanced lung disease, malaria, and sep...

External Links

•   NIH Clinical Center Detailed Web Page