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NCT00047996 Clinical Trial

Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

Sickle Cell Disease Clinical Trial

Official title:
Human Specimen Collection to Support Basic and Clinical Research

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT00047996
Other study ID # 030015
Secondary ID 03-H-0015
Status Recruiting
Phase
First received
Last updated
Start date November 4, 2002

Study information
Verified date April 12, 2024
Source National Institutes of Health Clinical Center (CC)
Contact Anna K Conrey, C.R.N.P.
Phone (301) 221-3016
Email anna.conrey@nih.gov
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general conditions under which sample collection will be performed.

Description:

The collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general conditions under which sample collection will be performed.

Recruitment information / eligibility
Status Recruiting
Enrollment 2000
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 100 Years
Eligibility - INCLUSION CRITERIA: Males or females of age 18 years and older can be included in the study. EXCLUSION CRITERIA: Individuals without sickle cell disease or other chronic anemias who wish to donate blood will be excluded if the hemoglobin is less than 10 g/dL for women or less than 12g/dL for men. Individuals with sickle cell disease or other chronic anemias will be excluded from donating blood samples if the hemoglobin is less than 6 g/dL. A participant s most recent CBC result, obtained in the past 12 months, will be used to determine eligibility. There are no exclusion criteria for participants donating saliva or urine.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States National Institutes of Health Clinical Center Bethesda Maryland
United States INOVA Fairfax Hosptial Fairfax Virginia

Sponsors (1)
Lead Sponsor Collaborator
National Heart, Lung, and Blood Institute (NHLBI)

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary evaluating the role of nitric oxide, inflammatory mediators, and endothelial function in inflammatory diseases of the vasculature such as sickle cell disease, coronary artery disease, pulmonary vascular or advanced lung disease, malaria, and sep...
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