Can Parecoxib Reduce Post-operative Ipsilateral Shoulder Pain?

Status Completed

Clinical Trial Summary

The purpose of this study is to compare the efficacy of parecoxib with placebo on the incidence and severity of postthoracotomy shoulder pain, the amount of analgesic requirement for relieving severity of postthoracotomy shoulder pain and adverse events associated with treatment.

Clinical Trial Description

The incidence of Post-operative Ipsilateral Shoulder Pain (PISP) varies from 21-97% after thoracic surgery, despite receiving effective thoracic epidural analgesia. This pain has been described as constant, aching in quality, unrelated to position change or respiration. Possible causes of shoulder pain includes injury of the phrenic nerve, the lateral decubitus position, transection of major bronchus or preexisting arthritis condition. The possibilities of prevention and management of PISP are taken into consideration. Thoracic epidural block will be performed in all patients before general anesthesia. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01288924
Study type	Interventional
Source	Chiang Mai University
Contact
Status	Completed
Phase	Phase 2
Start date	February 2011
Completion date	January 2016

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04930393` - Evaluating the Efficacy of PECS II Block Versus Axillary Ring Block in Rotator Cuff Repair Patients	N/A
Completed	`NCT03717753` - Rotator Cuff Pathway	N/A
Completed	`NCT04454671` - Ultrasound-guided Percutaneous Neuromodulation Versus Dry Needling in Shoulder Pain Treatment	N/A
Completed	`NCT06274827` - Electromyographic Analysis of Scapular Muscles During Closed Kinetic Chain Exercises	N/A
Not yet recruiting	`NCT05413213` - Ambulatory Rehabilitation Program in Patients With Degenerative Rupture of the Rotator Cuff Tendons of the Shoulder	N/A
Not yet recruiting	`NCT05043844` - Comparison of the Incidence of Shoulder Pain According to Postoperative Use of Abdominal Binder	N/A
Recruiting	`NCT02903719` - The Effect of Phrenic Nerve Block on Postoperative Shoulder Pain in Patients for Liver Resection.	Phase 4
Completed	`NCT02554968` - Reliability and Validity of Patient Reported Outcome Measures in Head and Neck Cancer
Completed	`NCT02777281` - Safe and Effective Shoulder Exercise Training in Manual Wheelchair Users With SCI	N/A
Recruiting	`NCT02242630` - Relationship to Dose of Triamcinolone Acetonide and Methylyprednisolone to Improvement in Subacromial Bursitis	N/A
Active, not recruiting	`NCT02843269` - Multiple-component Workplace FRamed Intervention to Decrease Occupational Muscle Pain - FRIDOM	N/A
Completed	`NCT02631395` - The Effect of a Shoulder Training Program to Prevent Shoulder Pain Among Girls in Junior Team Handball	N/A
Completed	`NCT01885377` - SWESS: The SWedish Exercise Shoulder Study in Primary Care for Patients With Subacromial Pain	N/A
Completed	`NCT01733914` - Contralateral Acupuncture in the Treatment of Chronic Shoulder Pain	Phase 2
Completed	`NCT01205542` - Work Place Adjusted Intelligent Physical Exercise Reducing Musculoskeletal Pain in Shoulder and Neck (VIMS) - Shoulder Function	N/A
Completed	`NCT01843660` - An Efficacy and Safety Study of Tramadol Hydrochloride-Paracetamol in Treatment of Moderate to Severe Acute Neck-Shoulder Pain and Low Back Pain	Phase 4
Completed	`NCT00743600` - Ultrasound Evaluation of the Rotator Cable and Associated Structures.	N/A
Completed	`NCT00679887` - Chronic Shoulder Pain Treated by Pressures With the Thumbs on the Trigger Points	Phase 1/Phase 2
Completed	`NCT04058522` - Treatment of Subacromial Shoulder Pain by Individual or Group Physiotherapy Following Corticosteroid Injection	N/A
Completed	`NCT03353272` - The Influence of a Cognitive Behavioral Approach on Changing Patient Expectations in Shoulder Pain	N/A