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Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome — GRAAL  

Short Bowel Syndrome Clinical Trial

Official title:
Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome : a Monocentric Pilot Study

Clinical Trial Summary

The purpose of this study is to assess the drug absorption of oral antibiotics in patients with short bowel syndrome.

Clinical Trial Description

When required, due to an infection, patients with short bowel syndrome will be treated with an intravenous antibiotic. The pharmacokinetic profile of that intravenous antibiotic will be determined. Once the full treatment with the intravenous antibiotic is over, the patient will be orally administered the same antibiotic, with determination of the oral pharmacokinetic profile, and both profiles will be compared, assessing the bioavailability of the oral antibiotic. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05302531
Study type Interventional
Source Central Hospital, Nancy, France
Contact Niasha MICHOT, MD
Phone +33383155108
Email n.michot@chru-nancy.fr
Status Recruiting
Phase Phase 1
Start date December 9, 2022
Completion date February 2025
View Details
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