The Cholelithiasis in Adults With Short Bowel Syndrome

Status Completed

Clinical Trial Summary

Short-term studies have shown that patients with short bowel syndrome (SBS) often develop cholestasis or cholelithiasis. In this retrospective cohort study, we aimed to define the incidence, risk factors, and clinical consequences of cholelithiasis in adults with SBS over an extended time period.

Clinical Trial Description

However, only limited data are available regarding cholelithiasis in patients with SBS. The prevalence of cholelithiasis in patients with SBS has been reported only in two studies. Furthermore, few studies have focused on identifying the risk factors for cholelithiasis in patients with SBS. Considering the marked improvements in medical care and nutrition support during the last 2 decades, the current incidence and risk factors for cholelithiasis in patients with SBS are unknown. The aim of the current study was to provide comprehensive, longitudinal, and long-term data on the incidence of symptomatic and asymptomatic cholelithiasis in a cohort of patients with SBS, in order to identify the prevalence, risk factors, and clinical consequences of cholelithiasis in patients with SBS to aid in the development of protective interventions. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04867538
Study type	Observational
Source	Jinling Hospital, China
Contact
Status	Completed
Phase
Start date	January 1, 2010
Completion date	December 31, 2020

View Details

See also
Status	Clinical Trial	Phase
Enrolling by invitation	`NCT05635747` - A 90 Day Observational Study as an Extension to the Phase 3,Open Labeled Exploratory Study of RELiZORB
Completed	`NCT01891279` - Elemental Formula in Neonates Post Small Bowel Resection: Improved Weaning From Total Parenteral Nutrition?	N/A
Completed	`NCT00930644` - Open-Label Study of Teduglutide for Subjects With PN-Dependent Short Bowel Syndrome (SBS)	Phase 3
Completed	`NCT01696656` - Prescription Pattern of Adjuvant Drugs and Vitamins in Patients Undergoing Long-term Home Nutritional Support for Intestinal Insufficiency	N/A
Completed	`NCT00910104` - Cholestasis Reversal: Efficacy of IV Fish Oil	Phase 2/Phase 3
Recruiting	`NCT04981262` - Improved Quality of Life in Children With Intestinal Failure	N/A
Completed	`NCT01930539` - Treatment of Vitamin D Deficiency in Intestinal Rehabilitation Clinic Patients With a Portable Ultraviolet B Lamp	N/A
Recruiting	`NCT05023382` - A Study of Teduglutide in Japanese People With Short Bowel Syndrome
Recruiting	`NCT04733066` - Quality of Life in Patients With Short Bowel Syndrome Treated Without and With Teduglutide - a Prospective Nested Matched Pair Analysis
Terminated	`NCT00742157` - Evaluate the Efficacy and Safety Growth Hormone, Glutamine and Diet in Patients With Short Bowel Syndrome (SBS)	Phase 4
Completed	`NCT04743960` - Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition	N/A
Completed	`NCT03690206` - Efficacy And Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome (SBS)	Phase 3
Terminated	`NCT02266849` - Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study	Phase 3
Completed	`NCT01306838` - Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy	Early Phase 1
Completed	`NCT01380366` - rHGH and Intestinal Permeability in Intestinal Failure	Phase 4
Completed	`NCT00248573` - Mechanisms of Adaptation in Human Short Bowel Syndrome	Phase 1/Phase 2
Withdrawn	`NCT03371862` - Liraglutide on Decreasing Parenteral Support in Short Bowel Patients (SLIPS)	Phase 2
Completed	`NCT04474743` - Malnutrition in Chronic Gastrointestinal Diseases, Cross-sectional Study
Completed	`NCT00067860` - Diet/Growth Factor Mechanisms of Gut Adaptation	Phase 2
Terminated	`NCT04046328` - Efficacy, Safety and Tolerability of Enteric-Coated Cholestyramine Capsules for Adult Short Bowel Syndrome	Phase 2