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Use of Pancreatic Enzymes in Short Bowel Syndrome — SBS  

Short Bowel Syndrome Clinical Trial

Official title:
Use of Pancreatic Enzymes in Short Bowel Syndrome

Clinical Trial Summary

Patients with short bowel syndrome have a high mortality rate that is mainly attributed to complications from central lines and long-term intravenous (IV) nutrition. There are few medical therapies to date that improve gut absorption in patients with short bowel syndrome. The primary objective of this study is to evaluate if absorption from the GI tract improves in subjects with short bowel syndrome following therapy with pancreatic enzymes.

Clinical Trial Description

This is an interventional study of subjects with short bowel syndrome to determine if enteral absorption improves following therapy with pancreatic enzymes. The study will assess enteral absorption and nutritional status at baseline through a series of stool tests, blood tests, and anthropometric measurements. Following approximately ten days of therapy with pancreatic enzymes, the study will reassess enteral absorption. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03097029
Study type Interventional
Source Children's Hospital of Philadelphia
Contact
Status Completed
Phase Phase 2
Start date March 24, 2017
Completion date February 1, 2019
View Details
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