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The Use of DPP-4 Inhibitors in Short Bowel Syndrome — DPP-4  

Short Bowel Syndrome Clinical Trial

Official title:
The Use of Dipeptidyl Peptidase-4 Inhibitor Influences the Absorption of Intestine in Short Bowel Syndrome

Clinical Trial Summary

The inhibition of Dipeptidyl peptidase-4 should increase the concentration of glucagone-like peptide 1 and 2, and the increase of the latter should increase the absorptive capacity of the intestine.

Clinical Trial Description

The only effective (to some extend drug) in short bowel syndrome is Glucacone-like peptide 4. Its price is, however, to high to really change the treatment strategy for intestinal failure. The Dipeptidyl peptidase-4 inhibitor, which a drug which is commonly used in the treatment of diabetes mellitus type II, should increase the concentration of glucagone-like peptide 1 and 2, and the increase of the latter should increase the absorptive capacity of the intestine. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02653131
Study type Interventional
Source Stanley Dudrick's Memorial Hospital
Contact
Status Terminated
Phase Phase 4
Start date January 2016
Completion date April 2020
View Details
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