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Clinical Trial Summary

Non-COVID-19 sepsis (Sepsis) has always been one of the common diseases in critically ill patients. The main treatment strategy is to kill pathogens and mitigate hyperinflammation. One study demonstrated that the supplementation with 576,000 IU cholecalciferol (vitamin D3) as a single dose in critically ill adults in the medical intensive care units (MICUs) can improve clinical outcomes, including acute physiology and chronic health evaluation II score (APACHE II), sequential organ failure assessment score (SOFA), and C-reactive protein (CRP). It is a three-year, multi-center, prospective, parallel, double-blind, randomized controlled clinical trial for 240 eligible subjects, with administrations of vitamin D3 576,000 IU or placebo every 24 hours for 3 days (72 hours) within 96 hours after intensive care unit (ICU) admission.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06447441
Study type Interventional
Source Chimei Medical Center
Contact Chin Ming Chen, professor
Phone +886 6-2812811
Email Chencm3383@gmail.com
Status Not yet recruiting
Phase N/A
Start date July 1, 2024
Completion date December 31, 2029

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