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NCT05602584 Clinical Trial

Effect of Immunophenotype on Prognosis of Sepsis

Sepsis Clinical Trial

Official title:
The Effect of Immunophenotype on Prognosis of Sepsis

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT05602584
Other study ID # EOIPOPOS
Secondary ID
Status Enrolling by invitation
Phase
First received
Last updated
Start date October 1, 2021
Est. completion date December 1, 2023

Study information
Verified date October 2022
Source Southeast University, China
Contact n/a
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

The popuse of this study is to assess the inflammatory immunophenotypes of sepsis patients are significantly correlated with prognosis, which may provide theoretical basis for precise immune regulation of sepsis.

Description:

The clinical characteristics and inflammatory/immune markers of sepsis patients were analyzed dynamically and followed up to one year after diagnosis. Through latent category analysis, cluster analysis and other inflammatory immunophenotypes, the clinical characteristics of different inflammatory immunophenotypes and their relationship with the long-term prognosis of sepsis were clarified.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 200
Est. completion date December 1, 2023
Est. primary completion date October 1, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:Patients with sepsis 3 diagnostic criteria were admitted to ICU; Aged 18 or above; Within 24 hours of diagnosis. - Exclusion Criteria:Malignant tumor; Autoimmune diseases; Diseases of the blood system; HIV infection; History of high-dose glucocorticoid use (hydrocortisone 200mg/d or other hormone with equivalent titer, more than one week); pregnancy -

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
China Department of Critical Care , Zhong-da Hospital Nanjing Jiangsu

Sponsors (1)
Lead Sponsor Collaborator
Southeast University, China

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary survival or death in 28 days observe wether the patients is survival or death in 28 days From date of randomization until the date of out of ICU or date of death from any cause, whichever came first, assessed up to 28 days
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