Comparative Study for the Validity of Various Severity Scoring System

Sepsis Clinical Trial

Official title:

Comparative Study for the Validity of Various Severity Scoring System in the Surgical Intensive Care Unit at Aswan University Hospital

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04683094
• Other study ID #: 449/3/20
• Status: Completed
• Start date: April 1, 2020
• Est. completion date: December 30, 2021

Study information

• Verified date: January 2022
• Source: Aswan University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Scoring systems for use in intensive care unit (ICU) patients have been introduced and developed over the last 30 years. They allow an assessment of the severity of disease and provide an estimate of in-hospital mortality

Description:

Severity scoring systems that are commonly used in critical care settings include Acute Physiology and Chronic Health Evaluation (APACHE), which was developed in the 1980s for predicting mortality, Simplified Acute Physiology Score (SAPS), and Mortality Probability Model (MPM). Although these scoring systems use different variables and weights for the classification of disease severity, they commonly monitor parameters such as heart rate, blood pressure, neurological state, and clinical data as these factors significantly deviate from physiological normality in the progression of critical disease. Old age and chronic disease are also captured by the scoring systems. Sequential Organ Failure Assessment (SOFA) score, which is based on organ failure over time to evaluate morbidity and multiple organ dysfunction is also used.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 200
• Est. completion date: December 30, 2021
• Est. primary completion date: December 30, 2021
• Gender: All
• Age group: 16 Years to 80 Years

Eligibility

Inclusion Criteria:

• newly admitted patients to the Surgical Intensive Care Unit with head trauma multiple trauma craniotomy sepsis preeclampsia - eclampsia postop. for vascular surgery Exclusion Criteria: less than 16 years old, readmitted to the ICU during the study period as only the first admission will be considered, ICU length of stay (LOS) less than 24 h

Related Conditions & MeSH terms

• Craniocerebral Trauma
• Eclampsia
• Head Trauma
• Multiple Trauma
• Polytrauma
• Pre-Eclampsia
• Sepsis
• Septic Shock

Locations

Country	Name	City	State
Egypt	Huda Fahmy	Aswan

Sponsors (1)

Lead Sponsor	Collaborator
Aswan University Hospital

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Acute Physiology and Chronic Health Evaluation (APACHE) IV		the first 24 hours after ICU admission
Primary	Simplified Acute Physiology Score (SAPS III)		the first 24 hours after ICU admission
Primary	Sequential Organ Failure Assessment (SOFA) score		the first 24 hours after ICU admission