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The Effect of Remote Ischemic Conditioning on the Microcirculation in Sepsis

Sepsis Clinical Trial

Official title:
Effects of Remote Ischemic Conditioning on Microcirculatory Alterations in Patients With Sepsis

Clinical Trial Summary

This study is an evaluation of the effect of Remote ischemic conditioning on sublingual microcirculation in patients with sepsis.

Clinical Trial Description

This prospective open-label trial is performed in mixed ICU in a tertiary teaching hospital. Investigators include patients with sepsis or septic shock within the first 24 h after ICU admission. Remote ischemic conditioning (RIC) procedure comprise three repetitions of brachial cuff inflation to 200 mmHg for five minutes following deflation to 0 mmHg for another five minutes. The procedure overall took 30 minutes. RIC is performed at inclusion and repeated 12 h and 24 h later. Sublingual microcirculatory measurements are obtained before and after each RIC procedure, using incidence dark field (IDF) device. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04644926
Study type Interventional
Source Lithuanian University of Health Sciences
Contact
Status Completed
Phase Phase 1/Phase 2
Start date February 1, 2018
Completion date September 1, 2020
View Details
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