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Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis

Sepsis Clinical Trial

Official title:
Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis

Clinical Trial Summary

In this research study we want to learn more about the characteristics of neutrophils that are present in the blood and secretions from a breathing tube of patients with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that are part of the body's immune system. Even though neutrophils are important in getting rid of germs, they also may be harmful to parts of the body by causing injury in the lungs in patients with sepsis. Neutrophils can change their character in sepsis. Because of this, it is important for doctors to know what kind of neutrophils are in the blood and secretions from the breathing tube of patients with sepsis so that they can work to develop therapies to prevent these cells from being harmful.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04103281
Study type Observational
Source Boston Children's Hospital
Contact Koichi Yuki, MD
Phone 617-355-6225
Email koichi.yuki@childrens.harvard.edu
Status Recruiting
Phase
Start date September 1, 2020
Completion date December 31, 2024
View Details
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