Sepsis Clinical Trial
Official title:
Long-term Outcome Among Survivors of Sepsis in China Assessed by EQ-5D
Sepsis is a common critical illness in Intensive Care Unit (ICU). With the continuous progress of severe medicine, the mortality rate of ICU hospitalization for sepsis has decreased, but the long-term prognosis is not satisfied. Due to the high long-term mortality, poor physical and mental health and cognitive impairment, the long-term quality of life decreases greatly, putting great burden on the family and society. Therefore, it is of great significance to understand the epidemiology and risk factors of the long-term prognosis of sepsis and find out how to improve the prognosis .
Sepsis is a clinical syndrome in which the body's host response to uncontrolled infection
leads to life-threatening organ dysfunction. In recent years, with the continuous improvement
of the early diagnosis ability of sepsis, the deepening of the understanding of
pathophysiology, and the continuous updating of treatment, the hospital mortality rate of
sepsis has decreased significantly. However, studies have shown that the prevalence of sepsis
is still increasing year by year, and the number of deaths due to sepsis is increasing.
Sepsis is the main cause of death in ICU patients.
Although the mortality rate of patients with sepsis is significantly reduced, the increasing
survival of patients with long-term outcome is not satisfied. All studies have shown that
patients with sepsis have a high long-term mortality, and the long-term physiological,
psychological, and cognitive function levels are reduced, which increases the economic burden
and mental burden of the family and society. The increasing number of discharges has been
considered a potential public health threat. In recent years, more and more researchers begin
to pay attention to the long-term outcome of sepsis survivors. But compared with other acute
or severe diseases, such as stroke, cancer, sepsis survivors has not been paid enough
attention.
Therefore, all stages of treatment and rehabilitation of sepsis require extensive social
attention. Continuous research and input are needed to explore predicting factors and
effective interventions to improve the outcome and help patients and their families return to
normal life,to reduce the social burden.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
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