Association Between Different Blood Groups and Sepsis in Preterm Infants

Sepsis Clinical Trial

Official title:

Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Clinical Professor

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03734978
• Other study ID #: BGaPS
• Status: Recruiting
• Start date: December 15, 2018
• Est. completion date: October 31, 2019

Study information

• Verified date: November 2018
• Source: Ankara University
• Contact: ufuk cakir
• Phone: 05058581781
• Email: drufukcakir[@]hotmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To investigate whether there is a relationship between sepsis and blood groups in preterm infants.This retrospective cohort study included preterm neonates born at <32 weeks of gestation with a birth weight <1500 g. Neonates were grouped by blood type (O, A, B, AB) and sepsis were compared among these groups.

Description:

This retrospective study was conducted on data collected between 1 January 2011 and 31 August 2018 in the neonatal intensive care unit (NICU) of the Health Sciences University Zekai Tahir Burak Women's Health Education and Research Hospital.

Neonates born at GA <32 weeks with birth weight (BW) <1500 g were included in the study.

Data pertaining to the neonates were recorded from medical records for each patient, and their ABO blood type was recorded.

The neonates were grouped by blood type (O, A, B, AB) and also separated into non-O (A, B, AB) and O groups and non-A (O, B, AB) and A groups for comparison of early and late onset sepsis.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 2000
• Est. completion date: October 31, 2019
• Est. primary completion date: February 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Preterm neonates born at <32 weeks of gestation with a birth weight <1500 g.

Exclusion Criteria:

• Neonates born with severe congenital defects, birth weight =1500 g and gestational age =32 weeks were excluded.

Related Conditions & MeSH terms

• Blood Group Antigen Abnormality
• Prematurity
• Sepsis

Intervention

Diagnostic Test:
• Diagnosis
biochemistry

Locations

Country	Name	City	State
Turkey	Zekai Tahir Burak Hospital	Ankara

Sponsors (2)

Lead Sponsor	Collaborator
Ufuk Cakir	Zekai Tahir Burak Women's Health Research and Education Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Association Between Different Blood Groups and Sepsis in Preterm Infants	The neonates were grouped by blood type (O, A, B, AB) and also separated into non-O (A, B, AB) and O groups and non-A (O, B, AB) and A groups for comparison of demographic characteristics, clinical features, and sepsis.	Through study completion, an average of 3 month