Controlled Fluid Resuscitation in Sepsis

Sepsis Clinical Trial

Official title: Controlled Fluid Resuscitation Strategy in Sepsis Patient

Status Not yet recruiting

Clinical Trial Summary

To evaluate two different strategy of fluid resuscitation in sepsis patients

Clinical Trial Description

Early goal-directed fluid therapy (EGDT) had been regarded as an important fluid therapy strategy in early sepsis or septic shock patients. In recent years, several randomized control studies showed the EGDT therapy cannot make a better outcome in sepsis patients compared to the standard therapy. A strategy of controlled fluid resuscitation had showed good outcome in critical illness such as severe acute pancreatitis, major trauma. But many aspects of the so-called controlled fluid resuscitation remained controversial. In a previous study on severe acute pancreatitis, we described a bundle of controlled fluid resuscitation which had showed an ideal result with higher survival rate. So, we are going to use the bundle on sepsis patients, and to see if it can bring a better out come in sepsis patients compared to the EGDT strategy. This study aims to determine a better strategy of fluid resuscitation in sepsis patients ;

Related Conditions & MeSH terms

• Sepsis
• Toxemia

• NCT number: NCT03214913
• Study type: Interventional
• Source: Ruijin Hospital
• Contact: Qiang En Mao, Doctor
• Phone: +86 18917762931
• Email: maoeq@yeah.net
• Status: Not yet recruiting
• Phase: N/A
• Start date: January 1, 2018
• Completion date: June 30, 2021