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NCT02768324 Clinical Trial

the Effect of Gut Microbiota on the Prognosis of Sepsis

Sepsis Clinical Trial

Official title:
the Effect of Gut Microbiota on the Prognosis of Sepsis

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT02768324
Other study ID # 13123412341
Secondary ID
Status Not yet recruiting
Phase N/A
First received May 10, 2016
Last updated March 7, 2017
Start date May 1, 2017
Est. completion date September 1, 2019

Study information
Verified date March 2017
Source Jinan University Guangzhou
Contact Li Deng, PhD
Phone 0086-18819351723
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Sepsis is a life-threatening condition that arises when the body's response to infection injures its own tissues and organs. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. Clinically, sepsis patients with diarrhea often result in a bad prognosis. Gut microbiota consists of a complex community of microorganisms that live in the digestive tracts of animals. The gut microbiota comprises the largest and most diverse reservoir of mutualistic microorganisms associated with animals. The aims of this study is to determin the effect of gut microbiota on the prognosis of Sepsis, by using 16s pyrosequencing, comparing the blood culture result.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 30
Est. completion date September 1, 2019
Est. primary completion date December 1, 2018
Accepts healthy volunteers No
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria:

- Subjects diagnosed with sepsis

- 18 years to 65 years of age

Exclusion Criteria:

- patients had complications such as acute cerebral infarction or acute myocardial infarction

- The use of antibiotics, pro-prebiotics within 3 months

- <18 years or >65 years

- History of intestinal surgery

- patients withdraw from this study

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Jinan University Guangzhou

Outcome
Type Measure Description Time frame Safety issue
Primary Discharged from ICU 7 days
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