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NCT02277977 Clinical Trial

Evaluation of Impaired Microcirculation During Septic Shock With Contrast Enhanced Ultrasound

Sepsis Clinical Trial

Official title:
Messung Von Mikrozirkulationsstörungen im Septischen Schock Mit Kontrastmittel- verstärkter Sonographie Evaluation of Impaired Microcirculation During Septic Shock With Contrast Enhanced Ultrasound

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT02277977
Other study ID # CUPIDDCH
Secondary ID
Status Withdrawn
Phase N/A
First received
Last updated
Start date November 2014
Est. completion date December 2015

Study information
Verified date August 2022
Source University Hospital Freiburg
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Microcirculatory disorders play a central role in the pathogenesis of sepsis and septic shock. Without adequate therapy that may lead to multi-organ failure and death. Therefore useful therapeutic measures aim to improve the microcirculation, to avoid tissue hypoxia and thus multiple organ failure or death. Clinically, the microcirculation can currently be indirectly evaluated using the diuresis and metabolic parameters (eg, lactate). The aim of the present study is to measure the microcirculation in septic shock by means of contrast-enhanced sonography of the calf muscles. For this purpose, the method is applied to 24 subjects during and after septic shock. It will be investigated in this study whether the microcirculation measurement with ultrasound contrast reflects the severity of the disease. As well as to evaluate whether the use of this diagnostic method could lead to better treatment of the septic shock.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date December 2015
Est. primary completion date November 2015
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - septic shock Exclusion Criteria: - myocardial infarction

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Contrast enhanced ultrasound
Contrat enhanced ultrasound during septic shock

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
University Hospital Freiburg

Outcome
Type Measure Description Time frame Safety issue
Primary Contrast transit time during and after septic shock 24 months
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