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Expression and the Clinical Significance of Neutrophil PD-L1 During Sepsis

Sepsis Clinical Trial

Clinical Trial Summary

Immunosuppression is the leading cause of death in septic patients. Neutrophils are classical components of innate immunology, but recent studies showed that neutrophils might display antigen presenting function and inhibit lymphocyte proliferation by expressing programmed cell death 1 ligand 1 (PD-L1). Whether neutrophils express PD-L1 and its role in immunosuppression during sepsis remain unclear.

Clinical Trial Description

n/a

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01976884
Study type Observational
Source Changhai Hospital
Contact
Status Completed
Phase N/A
Start date June 2011
Completion date January 2013
View Details
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