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Respiratory Muscle Dysfunction in Critically Ill Patients

Sepsis Clinical Trial

Clinical Trial Summary

Respiratory muscle dysfunction in critically ill patients is associated with elevated morbidity, including prolonged weaning from mechanical ventilation. The causes for respiratory muscle dysfunction in these patients is poorly understood and no effective treatment is available.

The general hypothesis of the present study is that in critically ill mechanically ventilated subjects respiratory muscle dysfunctions results from loss of myosin induced by activation of proteolytic cascades.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01104857
Study type Interventional
Source University Medical Center Nijmegen
Contact
Status Active, not recruiting
Phase N/A
Start date April 2010
Completion date April 2016
View Details
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