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NCT05185544 Clinical Trial

Combining Genomics and Imageomics to Predict the Sensitivity of Neoadjuvant Pemetrexed and Cisplatin Chemotherapy in Patients With Lung Adenocarcinoma

Sensitivity Clinical Trial

Official title:
Combining Genomics and Imageomics to Predict the Sensitivity of Neoadjuvant Pemetrexed and Cisplatin Chemotherapy in Patients With Lung Adenocarcinoma

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05185544
Other study ID # B2021-Zhan
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date January 1, 2022
Est. completion date December 31, 2024

Study information
Verified date December 2021
Source Shanghai Zhongshan Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Combining genomics and imageomics to predict the sensitivity of neoadjuvant pemetrexed and cisplatin chemotherapy in patients with lung adenocarcinoma

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 50
Est. completion date December 31, 2024
Est. primary completion date December 31, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria: - 1. Aged between 18 and 75 years; - 2. Lung adenocarcinoma; - 3. The patient is able to receive neoadjuvant pemetrexed and cisplatin chemotherapy - 4 .The patient is able to understand and comply with the study and has provided written informed consent. Exclusion Criteria: - 1. Patients with a history of lung surgery; - 2. Postoperative pathology showed non-primary lung cancer; - 3. Patients with a history of other tumors; - 4. Patients with severe complications (coronary heart disease, valvular heart disease, end-stage renal disease, severe liver cirrhosis); - 5. Unable to cooperate with the researchers because of dementia or cognitive decline - 6. Other situations that are not in conformity with the standards and requirements of this trial.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Neoadjuvant pemetrexed and cisplatin chemotherapy
neoadjuvant pemetrexed and cisplatin chemotherapy in patients with lung adenocarcinoma

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Shanghai Zhongshan Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary Tumor Regression Grade 1-2 Weeks after enrollment (after Surgery)
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