Sensitivity Clinical Trial
— SensoryFLOOfficial title:
Effects of Acute Intermittent Hypoxia on Sensory Function in Healthy Adults
Verified date | August 2023 |
Source | University of Florida |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Exposure to acute intermittent hypoxia (AIH) can facilitate of motor output but no studies of sensory effects has been reported.
Status | Completed |
Enrollment | 22 |
Est. completion date | July 6, 2020 |
Est. primary completion date | July 6, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 40 Years |
Eligibility | Inclusion Criteria: - 18 to 40 years of age Exclusion Criteria: - Diagnosis of cardiovascular disease (Hypertension, arrhythmias, coronary artery disease, congenital and valvar heart diseases) - Diagnosis of neuromuscular disease - Diagnosis of any neurological disease - Presence of concurrent medical illness including infection, fractures - Diagnosis of obstructive sleep apnea - Diagnosis of obstructive/restrictive lung disease - Diagnosis of exercise induced asthma - FEV1/FVC<80% and/or FVC<80% of predicted value indicating airway obstruction - Subjects on prednisolone therapy or selective serotonin reuptake inhibitor (SSRI) therapy will be excluded from the study as these pharmacological agents are known to amplify the effects of IH[22, 23] - Diagnosis of epilepsy or history of seizures and attention deficit disorders - Pregnancy - Diabetes - History of coagulation disorders - History of chronic pain - Body mass index(BMI)> 35kg/m2 - Subjects on prescription medicines such as beta blockers and other drugs that are prescribed in any of the exclusionary disorders listed above. |
Country | Name | City | State |
---|---|---|---|
United States | Unversity of Florida | Gainesville | Florida |
Lead Sponsor | Collaborator |
---|---|
University of Florida |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Sensory Function | Thermal thresholds. Average reported. | Every 10 minutes for 60 minutes post intervention, average reported | |
Primary | Temporal Sensory Summation | Temporal summation represents increases in ratings of pain intensity measured using a numeric pain rating scale (0-no pain to 100-worst pain imaginable) to repeated heat stimuli of the same intensity; that is, "summation" represents increases in participant ratings of pain despite the maintenance of a standard temperature and is calculated as the difference between pain rating 1 and pain rating 6. Positive difference scores indicate that pain reported increased over the 6 pulses of heat. Here, the average difference across participants and over time is reported. | Every 10 minutes for 60 minutes post intervention, average reported | |
Primary | Sensory Function - Pressure | Pressure threshold is the force at which the sensation of pressure first is considered painful by the participant, average reported | Every 10 minutes for 60 minutes post intervention, average reported |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04757454 -
Performance Indicators of the SARC-F Questionnaire in Acute Care
|
||
Completed |
NCT03792178 -
Evaluation of Post-operative Sensitivity of Bulk Fill Resin Composite Versus the Nano Resin Composite.
|
N/A | |
Recruiting |
NCT02834585 -
Magnetic Resonance Imaging or Ultrasound in Soft Tissue Tumors (MUSTT)
|
N/A | |
Not yet recruiting |
NCT06448169 -
Observational Study on the Sensitivity of Neoadjuvant Immunotherapy in Early Triple-Negative Breast Cancer
|
||
Recruiting |
NCT02825407 -
Creation and Characterization of Two Groups of Subjects to Evaluate Sensitivity
|
N/A | |
Terminated |
NCT05429307 -
Turkish Adaptation, Validity and Reliability of Exercise Sensitivity Questionnaire
|
||
Completed |
NCT04477408 -
Effect of Plantar Sensory Exercises on Balance and Fall Risk in Nursing Home Elderly
|
N/A | |
Recruiting |
NCT04505046 -
Validation of INSPiRED Innovative Smart Diagnostic Devices for the Detection of Parasites Infections.
|
||
Not yet recruiting |
NCT04762940 -
INTENSIVE TREATMENT WITH ROBOTIC PLUS VIBRATION IN STROKE
|
N/A | |
Completed |
NCT05474521 -
Evaluation of Illinois Agility Performance With Smartphone Applications: A Validity and Reliability Study
|
N/A | |
Completed |
NCT03568695 -
Detection of Chlamydia Trachomatis, Neisseria Gonorrhoeae and Mycoplasma Genitalium by Real-time Multiplex Polymerase Chain Reaction (PCR) After Pooling Pharyngeal, Anorectal and Urinary Samples
|
N/A | |
Completed |
NCT03031392 -
Sensitivity and Specificity of Peri-Implantitis-Related Parameters
|
N/A | |
Not yet recruiting |
NCT04091776 -
CT Scan in Per-trochanteric Fractures
|
N/A | |
Completed |
NCT03019224 -
Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening
|
Phase 4 | |
Not yet recruiting |
NCT05185544 -
Combining Genomics and Imageomics to Predict the Sensitivity of Neoadjuvant Pemetrexed and Cisplatin Chemotherapy in Patients With Lung Adenocarcinoma
|
||
Recruiting |
NCT03358992 -
Clinical Evaluation for Sarcoma Originated From Bone
|
||
Recruiting |
NCT05811559 -
Investigation of Sensory Processing Patterns of Elderly Individuals Who Have Had Hip Fracture Surgery
|
||
Recruiting |
NCT04700748 -
Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases
|
N/A | |
Completed |
NCT05024669 -
Efficacy of Desensitizers in Reducing Post-operative Sensitivity Following Composite Restorations
|
N/A |