The Effects of Microgravity on Human Sperm

Status Completed

Clinical Trial Summary

It has been described that microgravity affects cellular and molecular structures. Cell membrane, cytoskeleton, cytoplasm and nucleus have been found to be sensible to gravitational changes. Alterations in the male and female reproductive systems have also been reported in mouse and other animals. The effects of microgravity on human reproductive cells remain unknown. The main objective of this experimental study is to investigate the effect of simulated microgravity in human male reproductive cells under in vitro conditions. Induced microgravity conditions will be obtained with a smaller single-engine aerobatic aircraft that can provide parabolic flights. The main parameters to be analyzed are: sperm motility, vitality, DNA fragmentation and apoptosis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Semen Quality

Clinical Trial Details

NCT number	NCT03760783
Study type	Interventional
Source	Institut Universitari Dexeus
Contact
Status	Completed
Phase	N/A
Start date	November 20, 2018
Completion date	December 31, 2021

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See also
Status	Clinical Trial	Phase
Recruiting	`NCT03464656` - Oxidative Stress In Semen And Male Infertility	Phase 4
Terminated	`NCT01296230` - Varicocelectomy: Can Sex-hormones Predict Improvements in Semen Quality?	N/A
Completed	`NCT02667080` - Sperm Quality in Consecutive Sperm Samples After 4-7 Days and 2 Hours of Sexual Abstinence	N/A