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Semen Quality clinical trials

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NCT ID: NCT03760783 Completed - Semen Quality Clinical Trials

The Effects of Microgravity on Human Sperm

Start date: November 20, 2018
Phase: N/A
Study type: Interventional

It has been described that microgravity affects cellular and molecular structures. Cell membrane, cytoskeleton, cytoplasm and nucleus have been found to be sensible to gravitational changes. Alterations in the male and female reproductive systems have also been reported in mouse and other animals. The effects of microgravity on human reproductive cells remain unknown. The main objective of this experimental study is to investigate the effect of simulated microgravity in human male reproductive cells under in vitro conditions. Induced microgravity conditions will be obtained with a smaller single-engine aerobatic aircraft that can provide parabolic flights. The main parameters to be analyzed are: sperm motility, vitality, DNA fragmentation and apoptosis.

NCT ID: NCT03464656 Recruiting - Infertility, Male Clinical Trials

Oxidative Stress In Semen And Male Infertility

Start date: January 1, 2018
Phase: Phase 4
Study type: Interventional

The proposed research aims to study the effects of antioxidant therapy, commonly used in male infertility treatment, on semen analysis. Patients presenting with male infertility, who are found to have abnormal semen analysis shall be recruited to this study. They will be asked to provide a sample of semen for routine semen analysis and advanced semen tests including sperm DNA fragmentation and sORP before starting with antioxidant therapy and after 3-month treatment with antioxidants. After completing the data analysis, we intend to publish the study in high impact perr reviewed journals and present it in international conferences.

NCT ID: NCT02667080 Completed - Semen Quality Clinical Trials

Sperm Quality in Consecutive Sperm Samples After 4-7 Days and 2 Hours of Sexual Abstinence

Start date: April 2014
Phase: N/A
Study type: Interventional

The main purpose of the study is to assess to which degree a series of sperm parameters known to be associated with fertilization and implantation potential in artificial reproductive technology (ART) differ in consecutive sperm samples produced after 2-7 days and 2 hours of sexual abstinence in males from couples referring for ART treatment.

NCT ID: NCT01296230 Terminated - Infertility Clinical Trials

Varicocelectomy: Can Sex-hormones Predict Improvements in Semen Quality?

Start date: February 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the pre-operative levels of sex-hormones can be used to identify the varicocele patients who can expect improvements in their semen parameters following varicocelectomy.