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Clinical Trial Summary

This trial will study the safety and efficacy of subcutaneous semaglutide for the treatment of Systemic Sclerosis


Clinical Trial Description

Systemic Sclerosis (Ssc) is a rare, systemic autoimmune disease characterized by skin fibrosis and vasculopathy. In addition to the skin, it is a heterogeneous disease that affects multiple organs, including the cardiac, pulmonary, and gastrointestinal systems. This is a small prospective and open-label clinical trial of semaglutide in adults with systemic slceorsis. 10 systemic sclerosis patients will be recruited and receive semaglutide for 24 weeks. The primary endpoint of the study is the change in mRSS at 24 weeks of treatment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06149260
Study type Interventional
Source Second Xiangya Hospital of Central South University
Contact Rong Xiao, MD
Phone 13808425555
Email xiaorong65@csu.edu.cn
Status Recruiting
Phase Phase 1
Start date February 29, 2024
Completion date December 2024

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