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Seizures clinical trials

View clinical trials related to Seizures.

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NCT ID: NCT03742661 Active, not recruiting - Epilepsy Clinical Trials

Impact of SPEAC® System Data on Therapeutic Decisions Related to Convulsive Seizure Patients With a New Diagnosis

Start date: November 2, 2018
Phase: N/A
Study type: Interventional

This is an open label, randomized, prospective study of the impact on healthcare utilization of a surface Electromyography (sEMG) based seizure monitoring and alerting system for Veterans with a history of motor seizures (epileptic, non-epileptic or unknown) with upper extremity motor involvement, presenting with questionable spell characterization, taking place in the home setting.

NCT ID: NCT03548779 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2

NCGENES2
Start date: September 28, 2018
Phase: N/A
Study type: Interventional

The "North Carolina Clinical Genomic Evaluation by Next-gen Exome Sequencing, 2 (NCGENES 2)" study is part of a larger consortium project investigating the clinical utility, or net benefit of an intervention on patient and family well-being as well as diagnostic efficacy, management planning, and medical outcomes. A clinical trial will be implemented to compare (1) first-line exome sequencing to usual care and (2) participant pre-visit preparation to no pre-visit preparation. The study will use a randomized controlled design, with 2x2 factorial design, coupled with patient-reported outcomes and comprehensive clinical data collection addressing key outcomes, to determine the net impact of diagnostic results and secondary findings.

NCT ID: NCT03529045 Active, not recruiting - Epilepsy Clinical Trials

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System.

CORE-VNS
Start date: February 5, 2018
Phase:
Study type: Observational [Patient Registry]

Multicenter global post-market registry of subjects diagnosed with drug resistant epilepsy and treated with the VNS Therapy System.

NCT ID: NCT03474770 Active, not recruiting - Clinical trials for Focal Impaired Awareness Seizures

BIS-001-ER for the Treatment of Adult Focal Impaired Awareness Seizures

FIAS
Start date: April 10, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to examine safety signals and demonstrate seizure reduction in adults with FIAS treated with BIS-001ER as an add-on therapy in an in-patient and out-patient study design.

NCT ID: NCT03441867 Active, not recruiting - Epilepsy Clinical Trials

Neuroimaging Biomarker for Seizures

NIBMSZS
Start date: September 15, 2017
Phase: N/A
Study type: Interventional

This multi-site study will examine patients with epilepsy (ES) following head injury [i.e., posttraumatic epilepsy (PTE)] and posttraumatic psychogenic Non-epileptic seizures (PNES) and will compare them to patients with traumatic brain injury (TBI) who do not have seizures using functional neuroimaging.

NCT ID: NCT03313362 Active, not recruiting - Clinical trials for Psychogenic Seizures

Detecting PNES With Single-channel sEMG

Start date: November 3, 2017
Phase: N/A
Study type: Interventional

This is a prospective, comparative, multicenter study of subjects being admitted for standard of care therapy in Epilepsy Monitoring Units in the Veteran's Affair (VA) Medical Centers.

NCT ID: NCT03207685 Active, not recruiting - Epilepsy Clinical Trials

Generalized Seizure Detection And Alerting In The EMU With The Empatica Embrace Watch And Smartphone-Based Alert System

Start date: June 30, 2017
Phase: N/A
Study type: Interventional

To demonstrate safety and effectiveness of the Embrace device in identifying convulsive seizures (CS) and notifying a caregiver during patient hospitalization at an epilepsy monitoring unit (EMU).

NCT ID: NCT03191058 Active, not recruiting - Depression Clinical Trials

Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression

CREST-MST
Start date: June 26, 2018
Phase: N/A
Study type: Interventional

This trial aims to assess the efficacy and tolerability of Magnetic Seizure Therapy (MST) as an alternative to electroconvulsive therapy (ECT) for depression. Even with multiple medication trials, 30 - 40% of patients will experience a pharmacologically resistant form of illness. The ineffectiveness of current treatments for major depressive disorder (MDD) coupled with the economic burden associated with the disorder engenders a need for novel therapeutic interventions that can provide greater response and remission rates.

NCT ID: NCT03181945 Active, not recruiting - Seizures Clinical Trials

Duration of Anti-convulsant Therapy for Acute Symptomatic Seizure in Acute Encephalitis Syndrome

Start date: May 1, 2016
Phase: N/A
Study type: Interventional

There are no guidelines or studies evaluating duration of anti-epileptic drugs in central nervous system infections. The duration of anti-epileptic drug is extrapolated from traumatic brain injury in which duration of 1 weeks to 3 months is suggested. So the investigators plan to conduct this study to decide the optimal duration of anti-epileptic drug in acute symptomatic seizure in central nervous system infections

NCT ID: NCT03169751 Active, not recruiting - Epilepsy Clinical Trials

An Exploratory Trial Using sEMG to Differentiate PNES From Epileptic Seizures

Start date: September 1, 2017
Phase:
Study type: Observational

This is an observational study of subjects receiving standard of care therapy, while admitted to Epilepsy Monitoring Unit, Department of Neurology, General Hospital Hietzing with Neurological Center Rosenhügel. Additional monitoring provided by the SPEAC System will be compared to the gold standard, vEEG. The SPEAC System is being evaluated while being used in adjunct to standard of care.