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Seizures clinical trials

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NCT ID: NCT05257811 Completed - Sleep Clinical Trials

Earbud EEG Feasibility Study

PRIME
Start date: September 1, 2019
Phase:
Study type: Observational

The goal of this study is to characterize the ability of the NextSense ear-EEG device to detect pathologic electrographic signatures of epilepsy and physiologic signatures of sleep in subjects undergoing simultaneous inpatient continuous EEG monitoring, polysomnography, or ambulatory EEG monitoring at home.

NCT ID: NCT05248269 Enrolling by invitation - Epilepsy Clinical Trials

Thermocoagulation in Drug Resistant Focal Epilepsy

Start date: February 7, 2022
Phase: N/A
Study type: Interventional

Therapeutic thermocoagulation will be carried out in patients with drug-resistant focal epilepsy in cases where an epileptogenic zone is found and proven according to stereo-electroencephalography (SEEG) data.

NCT ID: NCT05246904 Completed - Clinical trials for Hearing and Vision Loss

Validating a Self-fitting Hearing Aid

Start date: March 17, 2022
Phase: N/A
Study type: Interventional

Eargo, Inc. has developed a hearing aid that contains self-fitting gain software that allows adults with mild-to-moderate hearing loss to test their hearing sensitivity and program hearing aids to match their measured hearing loss. Traditionally, hearing aids are custom programmed by a hearing health professional based on a professional hearing test. This technology has the potential to improve affordability and accessibility of hearing aids for adults with mild-to-moderate hearing loss. We propose to validate Eargo's self-fitting software in a clinical trial comparing self-fitting hearing aid outcomes to the same hearing aid fit by a professional following usual clinical best practice for fitting hearing aids.

NCT ID: NCT05241366 Completed - Clinical trials for Psychogenic Non-Epileptic Seizure

TMS vs Conventional Therapy for the Treatment of Functional Neurological Non Epileptic Seizure Disorder

Start date: February 14, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to compare the effect of Transcranial Magnetic Stimulation (TMS) versus treatment with selective serotonin reuptake inhibitors (SSRIs), in patients with diagnosis of Functional Neurological Non Epileptic Seizure Disorder (PNES).

NCT ID: NCT05239585 Not yet recruiting - Clinical trials for Neonatal Encephalopathy

Remote EEG Device for Identification of Risk for Neonatal Seizures

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to see if the use of wireless brain wave monitoring can be helpful for newborns and help their medical providers identify seizures earlier and to monitor for the risk for seizures.

NCT ID: NCT05230498 Recruiting - Clinical trials for Sensorineural Hearing Loss, Bilateral

Study of Sound and Speech Perception in New Cochlear Implanted Subjects Using or Not an Anatomy-based Fitting

Start date: February 15, 2022
Phase: N/A
Study type: Interventional

Main objective: Compare the recognition of environmental sounds with an anatomy-based fitting and with a default fitting adult patients newly implanted with a MED-EL cochlear implant. Secondary objectives: Compare speech recognition in quiet with an anatomy-based fitting and with a default fitting in adult patients newly implanted with a MED-EL cochlear implant. Compare speech recognition in noise with an anatomy-based fitting and with a default fitting in adult patients newly implanted with a MED-EL cochlear implant.

NCT ID: NCT05219617 Recruiting - Seizures Clinical Trials

Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults

Start date: April 28, 2022
Phase: Phase 3
Study type: Interventional

The primary objective is to evaluate the efficacy of carisbamate (YKP509) as adjunctive treatment in reducing the number of drop seizures (tonic, atonic, and tonic-clonic) compared with placebo in pediatric and adult subjects (age 4-55 years) diagnosed with Lennox Gastaut Syndrome (LGS).

NCT ID: NCT05219006 Completed - Ketogenic Dieting Clinical Trials

Ketogenic Diet Effects on the Frequency of Non Epileptic Seizures

Start date: July 15, 2021
Phase: N/A
Study type: Interventional

The objective of this study is to determine the effects of the ketogenic diet on the frequency of non-epileptic seizures in patients with functional neurological symptoms disorder compared to a healthy diet.

NCT ID: NCT05215366 Recruiting - Febrile Seizure Clinical Trials

Value of Copeptin Assay in Children With Febrile Seizures at Sohag University Hospital

Start date: January 7, 2022
Phase:
Study type: Observational

Febrile seizures are one of the most common clinical diseases in pediatric neurology. It occurs between 6 months and 6 years of age and occurs in ~2-5% of children. According to the age, frequency, duration, and type of seizures FS is divided into simple febrile seizures and complex febrile seizures Differentiation between febrile seizures and non-ictal events associated with fever such as shivering or dizziness is challenging. Therefore, precise diagnosis of FS after paroxysmal episodes associated with fever is often hindered by the lack of an objective biomarker With the widespread application of technologies, such as molecular biology, in medicine, some biomarkers for predicting or diagnosing FS have attracted attention. Imuekemhe et al in 1989 and 1996 found that lactic acid in the serum and cerebrospinal fluid of children with FS was significantly increased . Arginin-vasopressin hormone AVP released by the pituitary gland, has been shown to be involved in the thermoregulatory response to fever and convulsions Although AVP is unstable in the peripheral blood and, therefore, unsuited for diagnostic use the C-terminal portion of the AVP precursor copeptin has been recognized as a robust marker of AVP secretion . Wellman et al. found that the serum copeptin and Von Willebrand factor of children with FS were significantly higher than those of the control group .

NCT ID: NCT05214833 Recruiting - Health, Subjective Clinical Trials

Self-modulation of the Sense of Agency by Means of Real-time Neurofeedback

NF-Agency
Start date: February 1, 2022
Phase: N/A
Study type: Interventional

This study investigates whether the sense of agency is sensitive to self-regulation by means of EEG-based neurofeedback. During neurofeedback, the brain activity in response to a motor task is recorded in real-time and displayed back to the participants. The participants can therefore use this information to adapt their performance on the motor task.