TMS vs Conventional Therapy for the Treatment of Functional Neurological Non Epileptic Seizure Disorder

Psychogenic Non-Epileptic Seizure Clinical Trial

Official title: Controlled Clinical Trial of Transcranial Magnetic Stimulation Versus Conventional Therapy for the Treatment of Functional Neurological Non-Epileptic Seizure Disorder: A Pilot Study

Status Completed

Clinical Trial Summary

The aim of the study is to compare the effect of Transcranial Magnetic Stimulation (TMS) versus treatment with selective serotonin reuptake inhibitors (SSRIs), in patients with diagnosis of Functional Neurological Non Epileptic Seizure Disorder (PNES).

Clinical Trial Description

This study consists of a single-blind Randomized Controlled Clinical Trial comprised of 20 patients with diagnosis of Psychogenic Non Epileptic Seizures (PNES), distributed in 2 arms of 10 patients each. Patients (n=20) will be randomly assigned (using the block randomization method) to one of the groups. Both groups of patients will be receiving their usual medical treatment (SSRIs), one group will receive in addition a therapeutic scheme with active TMS, while the second group will receive the same scheme, but with a sham TMS coil to decrease the bias of placebo effect. ;

Related Conditions & MeSH terms

• Epilepsy
• Psychogenic Non-Epileptic Seizure
• Seizures

• NCT number: NCT05241366
• Study type: Interventional
• Source: El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
• Status: Completed
• Phase: N/A
• Start date: February 14, 2022
• Completion date: July 31, 2023