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Segmentectomy clinical trials

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NCT ID: NCT06132607 Completed - Lung Cancer Clinical Trials

3D Lung Reconstructions Using Open-source Software for Lung Cancer Surgery

3D-LUNG
Start date: December 21, 2022
Phase: N/A
Study type: Interventional

Preoperative three-dimensional (3D) lung reconstructions can reduce intraoperative blood loss, conversion rate, and operation duration. Commercial products predominantly provide these 3D reconstructions, hence the aim of this study was to assess the usability and performance of preoperative 3D lung reconstructions created with open-source software.

NCT ID: NCT05717803 Recruiting - Lung Adenocarcinoma Clinical Trials

Segmentectomy for Ground Glass-dominant Invasive Lung Cancer (ECTOP-1012)

Start date: February 15, 2023
Phase: Phase 3
Study type: Interventional

This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1012. The goal of this clinical trial is to confirm the theraputic effect of segmentectomy for ground glass-dominant invasive lung cancer with size of 2-3cm. The main questions it aims to answer are: - The 5-year disease-free survival of patients having ground glass-dominant invasive lung cancer with size of 2-3cm; - The post-operative lung function tests after receiving segmentectomy. Participants will receive segmentectomy as the surgical procedure.

NCT ID: NCT05525923 Not yet recruiting - Thoracic Surgery Clinical Trials

OpalGenix (TS) - Personalized Postoperative Pain Management Following Thoracic Surgery in Adults

Start date: October 1, 2023
Phase:
Study type: Observational

The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone, in adults following thoracic surgery. Major inpatient thoracic surgeries (TS) for lung disease are common and extremely painful surgeries and are associated with sever post-surgical pain, high incidence of chronic post-surgical pain (CPSP), excess opioid use, costly immediate postoperative opioid adverse events (AEs), and long hospital stays. This study is aiming to develop proactive risk prediction algorithms for precision surgical pain relief in adult TS patients through comparison of actual clinical outcomes with standard of care to predicted outcomes based on personalized risk assessments.

NCT ID: NCT05453721 Recruiting - Clinical trials for Non-small Cell Lung Cancer Stage I

Effect and Long-Term Outcomes of Indocyanine Green Fluorescence Imaging Method Versus Modified Inflation-Deflation Method in Identification of Intersegmental Plane(IMPLANE-0529)

IMPLANE-0529
Start date: August 4, 2022
Phase: N/A
Study type: Interventional

This study is a multi-center, prospective, randomized controlled clinical trial. The purpose is to compare the difference of indocyanine green fluorescence imaging method and modified inflation-deflation method in identifying intersegmental plane in segmentectomy, and provide high-level evidence for the selection of intersegmental plane identification method in early NSCLC segmental resection.

NCT ID: NCT05350137 Completed - Lung Cancer Clinical Trials

Application of Carbon Dioxide for Identifying the Intersegmental Plane in Thoracoscopic Segmentectomy

Start date: February 11, 2022
Phase: N/A
Study type: Interventional

With the increasing acceptance of routine computed tomography (CT) screenings, early-stage lung cancer detection is becoming more frequent. For ground glass opacity predominant early-stage lung cancer, segmentectomy can get the same oncological benefits as lobectomy. In addition, lung nodules that are highly suspected to be metastases can also be performed by segmentectomy to preserve more lung function. During the surgery, the rapid and precise identification of the intersegmental plane is one of the challenges. The improved inflation-deflation method is currently the most widely used method in clinical practice. According to the dispersion coefficient of the gas, the rapid diffusion properties of carbon dioxide would be expected to speed lung collapse and so facilitate surgery. The purpose of this study was to investigate the feasibility and safety of carbon dioxide on the appearance time of satisfactory and ideal planes during segmentectomy.

NCT ID: NCT04842578 Completed - Segmentectomy Clinical Trials

The Guidance of Thin Cross- Section of CT in Anatomic Segmentectomy

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

Three-dimensional (3D) simulation of pulmonary vessels and the space between the lesion and adjacent tissues is regarded improving the safety and accuracy of video-assisted thoracoscopic surgery (VATS) for segmentectomy for ground glass opacity (GGO) in lung. However, not every thoracic surgeon can handle the technique, in addition, the 3D reconstruction originate from the thin CT scan. Actually, the investigators found that, the reading and comprehension of the thin cross- section of CT can guide the accurate anatomic segmentectomy in most situations. The investigators designed a retrospective study to compare the reading of thin cross- section of CT with 3D reconstruction or without 3D reconstruction during the guidance of anatomic segmentectomy.

NCT ID: NCT04004494 Completed - Segmentectomy Clinical Trials

3D Reconstruction in Video-assisted Thoracoscopic Surgery (VATS) Segmentectomy

DRIVATS
Start date: July 1, 2019
Phase: N/A
Study type: Interventional

Anatomical variations of pulmonary vessel may cause serious problems during pulmonary segmentectomy. Three-dimensional (3D)computed tomography (CT) presents 3D images of pulmonary vessels and the tracheobronchial tree and may help operative planning. Retrospective studies have identified the importance of 3-dimensional CT in the field of pulmonary segmentectomy. And the aim of this study is to compare the usefulness of 3-dimensional CT with standard chest CT in preoperative planning of video-assisted segmentectomy.

NCT ID: NCT03227380 Recruiting - Segmentectomy Clinical Trials

Morphologic Study of the Intersegmental Plane After Fully Thoracoscopic Segmentectomy

Start date: March 31, 2017
Phase: N/A
Study type: Interventional

The objective of this study is to determine whether stapling adversely affects the pulmonary parenchyma and the vascularisation of the adjacent segments. The aim of our work is to explore by thoracic densitometry with contrast the spared segments after stapling of the intersegmental plan following a thoracoscopic segmentectomy, 3 or 6 months post-surgery. the investigator will assess venous drainage and the arterial vascularisation of the remaining segments, possible modifications of the adjacent parenchyma and whether there is a defect of pleuro-pulmonary adhesion (residual pneumothorax).

NCT ID: NCT03192904 Terminated - Segmentectomy Clinical Trials

Comparison of Energy Instruments and Stapling Device to Dissect Intersegmental Plane in Segmentectomy

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

According to published studies, there are two main approaches in the dissection of intersegmental plane: stapling devices and energy instrument separation. However, only a few retrospective studies focused on the perioperative outcomes of these two approaches, and there has been no definitive conclusion about which method is better. So the investigators want to conduct a prospective study, trying to figure out this problem.

NCT ID: NCT02816671 Active, not recruiting - Lobectomy Clinical Trials

MicroCutter Assisted Thoracic Surgery Hemostasis Registry

MATCH
Start date: June 2016
Phase:
Study type: Observational [Patient Registry]

The primary purpose of this prospective, open-label, multi-center observational registry with all-comers enrollment is to report on the use of the MicroCutter Stapler in a real world setting in thoracic surgical procedures. Procedures may be open or video assisted thoracic surgery (VATS) including robotic surgical cases. Clinicians will provide objective and subjective evaluation of the use of the stapler in their procedures.