Secondary Hyperparathyroidism Clinical Trial
Official title:
Quality of Life Change in Patients Undergoing Parathyroidectomy With Secondary Hyperparathyroidism Due to End-stage Renal Failure: a Prospective Cohort Study
The purpose of this study is to characterize the quality of life change in patients undergoing parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure.
Status | Not yet recruiting |
Enrollment | 80 |
Est. completion date | December 30, 2025 |
Est. primary completion date | December 30, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Age: =18 years old; - Patients scheduled for parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure Exclusion Criteria: • Patients refuse to participate |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Chunling Jiang |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Measure quality of life scores change with respect to time | Quality of life will be assessed by the 36-Item short form health survey scale, Subjects complete one response from a range of options for each of the 36 questions. A combination of item response is then aggregated to calculate a score for each of the eight dimensions listed. The scores for each dimension range from 0 to 100, with higher scores indicating better health status | up to 1 year | |
Secondary | Measure anxiety and depression score change with respect to time | The anxiety and depression were evaluated using Hospital anxiety and depression Scale (HADS). The HADS consists of 14 questions, with 7 items each for the anxiety and depression subscales. The score for each item ranges from 0 to 3 points, and scores are summed to yield a separate score for anxiety (HADS-A) and depression (HADS-D). | up to 1 year | |
Secondary | Measure bone pain scores change with respect to time | The bone pain is evaluated using numerical rating scale (NRS). NRS scores range from 0 to 10 points, with 0 points representing no pain, 1-3 points representing mild pain, 4-6 points representing moderate pain, 7-9 points representing severe pain and 10 points representing the strongest pain. | up to 1 year | |
Secondary | Length of hospital stay | Determined by the number of days from admittance to discharge | through study completion, an average of 1 week |
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