the Comparison of Multifocal Contact Lenses and Bifocal Spectacles for Congenital Cataracts
In this study, the investigators provide participants who had congenital cataract the multifocal contact lenses and bifocal spectacles in the purpose of seeking out a better way to make a definite diagnosis with high efficiency and accuracy, and report a prospective, randomized controlled study aiming at comparison of multifocal contact lenses and bifocal spectacles.
NCT03260764 — Multifocal Contact Lenses
Status: Active, not recruiting
http://inclinicaltrials.com/multifocal-contact-lenses/NCT03260764/
Establishment of the Mathematic Model of Non-genetic Risk Factors of Congenital Cataracts
Prevention and treatment of the reversible childhood blindness, including congenital cataracts (CC), has been listed as a significant component of the international programme "VISION 2020 - the Right to Sight" launched by WHO in 1999. However, there is still a lot of unsolved problems regarding to CC, especially in developing countries, such as the delayed presentation and treatment to the hospitals, the lack of specialized treatment departments, and the poor treatment prognosis. With the two children policy opened in China in 2016, many CC parents hesitate to have a second child due to the potential high risk of CC. Date on detailed clinical characteristics of the CC children, including the demography, pregnancy-labor history, and living condition, are crucial for developing the national screening strategies of CC in Pregnant women. However, to our knowledge, it still lacks of thus large population-based and comprehensive investigations of the characteristics of CC children in developing countries.
NCT03215186 — Cataract
Status: Recruiting
http://inclinicaltrials.com/cataract/NCT03215186/
Subfoveal Choroidal Thickness After Femtosecond Laser-assisted Cataract Surgery for Age-related Cataracts
To compare the effects of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) on subfoveal choroidal thickness (SFCT) in age-related cataracts.
NCT02895074 — Cataract
Status: Completed
http://inclinicaltrials.com/cataract/NCT02895074/
Risk of Radiation-induced Cataracts Among Interventional Cardiology Staff- Cataracts Attributed to Radiation in the CaTh Lab: The IC-CATARACT Study
The goal of the present study is to evaluate the prevalence of radiation-associated lens opacities among interventional cardiology staff members (such as physicians, technicians, and nurses) and determine its association with occupational history. The hypothesis of the study is that interventional cardiology staff will have high prevalence of radiation-induced lens opacities, which will be higher than non-interventional cardiology staff and will correlate with the estimated cumulative lifetime dose.
NCT02837562 — Cataract
Status: Withdrawn
http://inclinicaltrials.com/cataract/NCT02837562/
Effect of the Timing of Lens-removal Cataract Surgery on Postoperative Complications Rate Among Patients With Bilateral Congenital Cataracts
Congenital cataract is an important treatable cause of visual handicap in childhood throughout the world. Successful management of childhood cataract is dependent on individualized treatment strategies and rigorous postoperative supervision for adverse complication. In this trial, we aimed to compare the difference of postoperative outcome between surgical timing at age of 3 month and 6 month. Patients enrolled into the study will be followed for two year and will have study visits at 1 day, 1 week, 1 month, 3 month, 6 month, 9 month, 12 month, 18month and 24month postoperatively.
NCT02581046 — Cataract
Status: Completed
http://inclinicaltrials.com/cataract/NCT02581046/
Femtosecond Laser Assisted Cataract Surgery in Intumescent Cataracts
The purpose of the study is to compare femtosecond laser-assisted capsulotomy to manual capsulorhexis in patients with intumescent cataracts. An intumescent cataract is defined as a cataract with a pressurized capsular bag.
NCT02403206 — Intumescent Cataract
Status: Completed
http://inclinicaltrials.com/intumescent-cataract/NCT02403206/
Retrospective Patient Satisfaction Survey in Subjects With Tecnis Intra Ocular Lenses Cataracts Surgery
Define what factors correlate with higher degrees of patient satisfaction and dissatisfaction among patients who have recently undergone cataract surgery.
NCT01946581 — Cataract
Status: Recruiting
http://inclinicaltrials.com/cataract/NCT01946581/
Antioxidants for Prevention of Cataracts Follow-up Study
Aravind Eye Hospital and the University of California, San Francisco (UCSF) Proctor Foundation collaborated on the Antioxidants for the Prevention of Cataract Study from 1997-2002. (1) In the study, 798 participants aged 35-50 years were enrolled from 5 rural villages, and randomized to thrice weekly antioxidants (vitamin C, 500 mg; beta carotene, 15 mg; and alpha-tocopherol, 400 IU) or placebo. After 5 years of supplementation, there was no significant difference in cataract formation between the antioxidant group and placebo. In this follow-up study, we will return to study villages to determine whether rates of cataract surgery are different in the 2 groups. 1. Gritz DC, Srinivasan M, Smith SD, et al. The Antioxidants in Prevention of Cataracts Study: effects of antioxidant supplements on cataract progression in South India. The British journal of ophthalmology 2006;90:847-51.
NCT01664819 — Cataract
Status: Completed
http://inclinicaltrials.com/cataract/NCT01664819/
Study of the Occupational Risk of Radiation-induced Cataracts Among Cardiologists
The purpose of this study is to test the existence of an increased risk of cataracts among interventional cardiologists as compared to cardiologists not exposed to X-rays.
NCT01061463 — Cataracts
Status: Completed
http://inclinicaltrials.com/cataracts/NCT01061463/
Clinical and Molecular Studies in Families With Congenital or Hereditary Cataracts
This study will explore the clinical and hereditary (genetic) features of inherited cataracts. A cataract is a clouding of the eye lens, which focuses light on the back of the eye. When the lens becomes cloudy and does not let light through, vision is impaired. Cataracts may be associated with vision problems alone, or with other problems, such as changes in facial appearance or skin problems. A better understanding of these genetic conditions may help in the development of better diagnostic tests. Patients with inherited cataracts and their family members may be eligible for this study. Participants will be drawn from patients enrolled in other studies of inherited cataracts at the NEI and collaborating clinics. Participants will undergo the following tests and procedures: - Medical and surgical history; - Verification of diagnosis; - Construction of a family tree regarding familial vision problems; - Complete eye examination, including dilation of the pupils and photography of the lens, tests of color vision and field of vision, and of the ability to see in the dark; - Blood sample collection (20 ml, or 4 teaspoons) for genetic studies of hereditary cataracts.
NCT00056771 — Cataract
Status: Completed
http://inclinicaltrials.com/cataract/NCT00056771/