Process of Regulation in Addictions: Vulnerability Emotional Factors to Craving
The aim of this study is to have a better understanding of the relationship between self-controle difficulties (and more specifically the inhibition deficit in impulsivity), emotional regulation disorders such as alexithymia and craving.This study will be the first in France to specify the interactions between self-regulkation processes dysfunctions and emotional dysfunctions in craving.
NCT05076201 — Craving
Status: Recruiting
http://inclinicaltrials.com/craving/NCT05076201/
Repeated Suicide Attempts in a Patient Suffering From Addiction to Tramadol: a Case Report
In France, over the last years the use weak opioid analgesics decreased́, whereas that of strong opioid analgesics (OFMA). Hospitalizations for opioid overdose increased́ by 128% from 2000 to 2015, and deaths related to prescribed opioid overdose increased significantly, by 161%, from 2000 to 2014.In addition, recent studies suggest a link between opioid system dysfunction and suicidal behavior. In parallel, studies are emerging showing the potential interest of using Tramadol as an antidepressant. Indeed, this opiate analgesic also acts on the serotonergic and dopaminergic systems, and would have an antidepressant effect.Thus, the investigators can legitimately wonder whether the use of Tramadol as an antidepressant might not pose a problem in patients at risk of suicide. This study aims to describe a clinical case of a patient hospitalized in the Department of Psychiatric Emergency and Post-Emergency (Montpellier University Hospital) who developed a severe addiction to Tramadol (consumption up to 5 times the maximum recommended dose per day) and evaluate whether this may have increased her suicidal risk, in order to warn prescribers about the suicidal risk of Tramadol.
NCT05075291 — Suicide, Attempted
Status: Completed
http://inclinicaltrials.com/suicide-attempted/NCT05075291/
Investigation of the Effect of Internet Addiction Level on Thumb Pressure Pain Threshold, Hand Strength and Manual Dexterity in University Students
The internet, which has become a part of our daily life; serves many purposes such as quick access to information, e-mail, and chat, banking and shopping, having a good time, using social networking sites. Internet addiction, which was first defined by Ivan Goldberg in 1996, is defined as the inability to control internet use, which causes pressure, feelings of anxiety, and dysfunctional behaviors in daily life activities. Social media, digital games and smartphone addiction are among the addiction types whose active ingredient is the internet, and internet addiction is expressed as a whole, regardless of the type of addictive application or activity. Considering that internet use is common among young people, one of the risk groups in terms of internet addiction is university students. As a matter of fact, Günay et al. stated that approximately 8% of university students are at risk of internet addiction. In the literature, musculoskeletal problems and pain in the thumb and related joints, reduction in pinch strength, and hand function have been reported with smartphone use. In addition, a significant relationship was found between the time spent surfing the Internet and pain at the base of the thumb. However, to the best of our knowledge, no study has been found that examines the effect of internet addiction level on thumb pain threshold, hand strength and manual dexterity in university students. The aim of our research is to determine the level of internet addiction in university students and to examine the effect of internet addiction level on thumb pressure pain threshold, hand strength and manual dexterity.
NCT05065723 — University Students
Status: Completed
http://inclinicaltrials.com/university-students/NCT05065723/
Assessment of ADDICTion to Psychoactive Drug Use in Intensive Cardiac Care Units - The ADDICT-CCU Study
Background: Illicit drug use is a growing issue in Europe and leading cause of acute cardiac events in patients admitted to intensive cardiac care units. Indeed, cardiovascular complications are one of the main causes of death due to illicit drug use. However, its prevalence in patients hospitalized in intensive cardiac care units is unknown. Objectives: This large multicenter prospective study will assess the prevalence of illicit drug use in consecutive patients hospitalized in intensive cardiac care units by urine drug assay. Eligibility: - Patient over 18 years old admitted to intensive Cardiac Care Unit (CCU) for any reason. - Without hospitalization for a planned interventional procedure. - Without hospitalization for more than 24 hours at any hospital facility before admission to the CCU. Design: - Multicentre cohort study with a prospective enrolment of all consecutive patients admitted to the CCU to assess the prevalence of illicit drug use in 40 centers throughout France. - Participants will be screened with a physical exam, medical history and addiction survey. - Participants will be screened for drug use by urine drug assay (NarcoCheck®, Kappa City Biotech SAS, Montluçon, France) and for tobacco by standardized exhaled carbon monoxide (CO) measurement with a CO-Check Pro device (Bedfont Scientific Ltd, Kent, UK). - Participants will be followed at 6 months of follow-up to assess the occurrence of cardiovascular events.
NCT05063097 — Substance-Related Disorders
Status: Active, not recruiting
http://inclinicaltrials.com/substance-related-disorders/NCT05063097/
The Effect of Online Group Motivational Interviewing on Eating Behaviour, Healthy Lifestyle Behaviours and Quality of Life in Nursing Students With Food Addiction: Randomized Controlled Study
The aim of this study is to determine the effect of online group motivational interviewing (MI) on eating behavior, healthy lifestyle behaviors and quality of life in nursing participants with food addiction at three state universities in Ankara. The population of the research will be those who meet the diagnostic criteria for food addiction according to the Yale Food Addiction Scale. The research sample size was calculated with the G* Power package program. As a result of the power analysis, a total of 52 participants, 26 for the intervention group and 26 for the control group, were found sufficient for the sample with 90% power, 5% margin of error and 0.2065 effect size. Considering that the number of participants would decrease during the research process, the number of samples was increased by 10% to a total of 58 university participants, 29 of which were interventions and 29 were controls. Among the participants who meet the food addiction criteria, the participants who meet the inclusion criteria and agree to participate in the research will be randomly assigned to the intervention and control groups (n1=29; n2=29). After these participants are stratified according to the change (pre-contemplation and contemplation stage) phase, a simple random assignment process within the strata will be done by an independent researcher to avoid selection bias. Random assignment will be done through a simple random numbers table. The independent researcher who does not know which group is the intervention group and which group is the control group will collect the data. Data collection tools will be applied to the participants in the intervention and control groups in the pre-MI session, the post-MI session, and 2 months later in the follow-up session. It was planned to apply 5 sessions of MI to the intervention group, and to follow-up 2 months after the interviews were completed. No application will be made to the participants in the control group, and at the end of the study, a seminar on food addiction and quality of life will be given to the participants.
NCT05046938 — Food Addiction
Status: Completed
http://inclinicaltrials.com/food-addiction/NCT05046938/
Smartphones for Opiate Addiction Recovery
Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus recently become a major NIDA policy goal. The 5-minute battery indicates the numerical probability that a patient will reuse illicit opiates within the next 7-10 days.
NCT05033028 — Opioid-use Disorder
Status: Recruiting
http://inclinicaltrials.com/opioid-use-disorder/NCT05033028/
A Phase 2 Study to Investigate Use of Transcranial Direct Current Stimulation (tDCS) to Reduce Craving in Cocaine Addiction
Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation in which low level electrical currents are applied to the scalp in order to alter brain function. In a prior Phase-I study, the research team demonstrated feasibility of self-administration of a home-tDCS prototype in 14 patients that applied 15 sessions for each patient at an outpatient center.
NCT04994821 — Cocaine Dependence
Status: Recruiting
http://inclinicaltrials.com/cocaine-dependence/NCT04994821/
Repetitive Transcranial Magnetic Stimulation in Treatment of Taiwanese Amphetamine Users: A Pilot Study
The study aims to test whether transcranial magnetic stimulation (TMS) improves the craving, depression, anxiety and cognitive function during the abstinent period of methamphetamine users.
NCT04993300 — Depression, Anxiety
Status: Completed
http://inclinicaltrials.com/depression-anxiety/NCT04993300/
Prevalence of Internet Addiction and Internet Gaming Disorder Among Assiut University Students
identifying the Prevalence of internet addiction and internet gaming disorder among Assiut university students
NCT04965363 — Internet Gaming Disorder
Status: Not yet recruiting
http://inclinicaltrials.com/internet-gaming-disorder/NCT04965363/
Prevalence of Internet Gaming Addiction in Adolescent
Excessive problematic use of the internet has been a topic of discussion in the academic literature for many years and has gained more attention recently. The majority of those at risk are in early adulthood. Pathological internet use (PIU) is also termed internet addiction disorder (IAD), with both terms used to link internet use with addiction terminology. Consistent with other psychiatric conditions such as depression symptoms, PIU prevalence rates among adolescents vary widely from as low as 0.3% to 38%. Likewise, PIU prevalence among college students (young adults) showed a wide variation ranging from 3% to 34%, worldwide. Nowadays, internet gaming addiction became a problematic issue in adolescent. This is a case -control study, aimed to evaluate the prevalence and risk factors of internet gaming addiction among adolescents and its relationship with emotion regulation and comorbid psychiatric disorders.
NCT04960254 — Adolescent Behavior
Status: Not yet recruiting
http://inclinicaltrials.com/adolescent-behavior/NCT04960254/