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Scoliosis clinical trials

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NCT ID: NCT01852747 Terminated - Scoliosis Clinical Trials

Comparison of Actifuse ABX and Local Bone in Spinal Surgery

Start date: March 2013
Phase: Phase 4
Study type: Interventional

This study is being done to compare people who had a standard of care spinal fusion using part of their local bone graft (a small amount of bone from the region of the spine where the fusion is occurring) to correct an adult spinal deformity and people who will have a standard of care spinal fusion using a mixture of Actifuse ABX® (a market approved bone graft substitute) and a local bone graft (a small amount of bone from the region of the spine where the fusion is occurring). This study will compare the outcomes of both groups to help the Orthopaedic surgeon conducting spinal fusions in the future. Investigators expect that Actifuse ABX® will be as good if not better than just a local bone graft.

NCT ID: NCT01370057 Terminated - Scoliosis Clinical Trials

The Use of Thoraco-lumbo-sacral Orthoses (TLSOs) in the Treatment of Adolescent Idiopathic Scoliosis (AIS)

Start date: May 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the risk of curve progression in Adolescent Idiopathic Scoliosis for subjects treated with bracing as compared to those without bracing.

NCT ID: NCT01089140 Terminated - Clinical trials for Non-idiopathic Scoliosis

Non-Idiopathic Scoliosis Treated With Tranexamic Acid

Start date: November 2014
Phase: Phase 2
Study type: Interventional

Investigation of tranexamic acid (TXA) for reducing perioperative blood loss and transfusion requirement in pediatric patients with secondary scoliosis undergoing posterior spinal fusion.

NCT ID: NCT00577226 Terminated - Scoliosis Clinical Trials

Shilla Growth Permitting Spinal Instrumentation System for Treatment of Scoliosis in the Immature Spine

Start date: April 2005
Phase: N/A
Study type: Observational

The objective of this study is to retrospectively and prospectively review patients who have undergone this technique looking at age of the patient, magnitude of the curve preoperatively, postoperatively and over time, diagnosis, pulmonary function, surgical procedures, complications, and spinal growth. The hypothesis is that Shilla growth permitting spinal instrumentation coupled with a surgical technique of aggressive correction of the apex of the scoliotic curve wil allow for natural growth of the spine in a guided fashion with a limited number of future surgeries required.

NCT ID: NCT00448448 Terminated - Clinical trials for Adolescent Idiopathic Scoliosis

Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST)

BrAIST
Start date: February 2007
Phase: N/A
Study type: Interventional

Adolescent idiopathic scoliosis (AIS) is a structural curve of the spine with no clear underlying cause. Bracing is currently the standard of care for preventing curve progression and treating AIS. However, the effectiveness of bracing remains unclear. The purpose of this study is to compare the risk of curve progression in adolescents with AIS who wear a brace versus those who do not and to determine whether there are reliable factors that can predict the usefulness of bracing for a particular individual with AIS.