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Scoliosis clinical trials

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NCT ID: NCT00890227 Completed - Scoliosis Clinical Trials

Incidence of Proximal Junctional Kyphosis (PJK) in Long Posterior Spinal Fusion: A Study Comparing Traditional Open Surgery to Minimally Invasive Percutaneous Technique at the Proximal Fusion Levels

Start date: June 2009
Phase: N/A
Study type: Interventional

This research is being done to compare two methods of surgery to treat scoliosis and/or kyphosis of the spine.

NCT ID: NCT00886652 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

An Aerobic Exercising Program on Respiratory Muscle Strength in Patients With Adolescent Idiopathic Scoliosis

Start date: January 2008
Phase: N/A
Study type: Interventional

Adolescent Idiopathic Scoliosis (AIS) can change the respiratory dynamics and performance of the inspiratory and expiratory muscles, affecting ventilatory capacity. This was a randomized, controlled, open study to test the impact of a physiotherapeutic program of aerobic exercises on respiratory muscle strength, in patients with adolescent idiopathic scoliosis. Patients with AIS were randomly assigned to the aerobic exercise-training program group or the no treatment group. There was a significant increase in Pimax and Pemax in the group which received physiotherapy.

NCT ID: NCT00880607 Completed - Pain Management Clinical Trials

Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion

Start date: December 2008
Phase: Phase 4
Study type: Interventional

This study plans to learn more about preventing pain in children who are having posterior spinal fusion surgery using two different kinds of morphine (a pain medicine). Also, this study plans to learn about individual differences in the how the different kinds of morphine work in children. Subjects are being asked to be in this research study because they are having spinal fusion surgery, will have pain some of the time and will be getting morphine during and after surgery to help control their pain.

NCT ID: NCT00854828 Completed - Scoliosis Clinical Trials

A Multicenter Prospective Study of Quality of Life in Adult Scoliosis

ASLS
Start date: April 2010
Phase: N/A
Study type: Interventional

This is a multicenter study evaluating the effectiveness of nonoperative and operative treatments. The investigators wish to identify important clinical and radiographic determinants of outcomes in the management of adults with symptomatic lumbar scoliosis (ASLS). Note: Enrollment was complete July 2014. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) funding ended 2/28/17. We continue to follow enrolled subjects while we seek additional funding to follow all subjects through 8 years.

NCT ID: NCT00737997 Completed - Scoliosis Clinical Trials

Effect of Early Morphine Administration on the Development of Acute Opioid Tolerance During Pediatric Scoliosis Surgery

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine if morphine administered by bolus before initiating Remifentanil by infusion decreases the incidence of acute post-operative opioid tolerance as demonstrated by decreased post - operative morphine consumption in children undergoing scoliosis surgery.

NCT ID: NCT00726128 Completed - Trauma Clinical Trials

Patient Outcomes Evaluation of the EBI Vuelock™ Anterior Cervical Plate System

VueLock
Start date: August 1998
Phase:
Study type: Observational

To prospectively collect radiographic and outcome data on patients who are having cervical spine fusion surgery with the VueLock™ Anterior Cervical Plate System

NCT ID: NCT00684112 Completed - Scoliosis Clinical Trials

Analgesic Effects of Gabapentin After Scoliosis Surgery in Children

Start date: May 2008
Phase: Phase 3
Study type: Interventional

The primary aim of this study is to determine whether the use of gabapentin will improve postoperative analgesia and reduce opioid consumption and side effects in children undergoing corrective spinal surgery for idiopathic scoliosis. Secondary aims are to evaluate whether use of gabapentin reduces pain scores, decreases postoperative nausea and vomiting, decreases persisting pain and improves patient satisfaction.

NCT ID: NCT00671931 Completed - Scoliosis Clinical Trials

Susceptibility of Motor-Evoked Potentials to Varying Targeted Blood Levels of Dexmedetomidine

Start date: April 2007
Phase: Phase 1
Study type: Interventional

Reduction of the spinal cord injuries during scoliosis surgery is a major goal of the anesthesia and surgical team. Despite improvement in scoliosis surgery over the years, the development of neurological deficits remains the most feared complication of spine surgery. During scoliosis surgery it is very important to monitor the spinal cord to detect spinal cord injury with surgical manipulation. Continuous or intermittent intraoperative electrophysiological monitoring (neuron-monitoring) is used routinely during these procedures to provide the surgeon with information concerning the integrity of neurological structures at risk. All neuron-monitoring modalities are affected by the anesthetic regimen used. Of the various intravenous anesthetic drugs, the combination of propofol, remifentanil and dexmedetomidine appear to impact neuron-monitoring the least. The current anesthetic practice is to use the three drugs in combination at doses that do not depress the signals but there is no data relating targeted dexmedetomidine and propofol blood levels to neuron-monitoring signals. The lack of data results in wide variability in dosing with consequent variability in patient response. Hypothesis: Clinically relevant blood levels of dexmedetomidine will affect the amplitude of transcranial motor-evoked potentials (TcMEP) either independently or by interaction with propofol in a dose dependent manner.

NCT ID: NCT00510575 Completed - Scoliosis Clinical Trials

Surgical Outcomes Using Variable Rod Diameters in the Treatment of Idiopathic Scoliosis

Start date: May 2007
Phase: Phase 4
Study type: Interventional

There are two rod sizes routinely used for the correction of juvenile and adolescent idiopathic scoliosis, 5.5mm and 6.35mm, typically stainless steel. Currently there is no scientific evidence supporting the superiority of one size rod relative to the other. This study will evaluate the amount of radiographic correction obtained using the 5.5mm versus the 6.35mm spinal instrumentation rods.

NCT ID: NCT00508066 Completed - Scoliosis Clinical Trials

Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery

Start date: May 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of continuous local anesthetic delivery on the immediate post-op recovery of patients undergoing spinal fusion surgery for congenital or idiopathic scoliosis.