Bizarreness and Anomalous Self Experiences in Schizophrenia — BASES  

Schizophrenia Clinical Trial

Official title: Bizarreness and Anomalous Self Experiences in Schizophrenia: Pilot Study on Diagnostic Decision-Making

Status Recruiting

Clinical Trial Summary

Several authors suggest that the specific experience felt in clinical encounter, called Praecox Feeling, is directly linked to the psychopathology of Schizophrenia.

However, determining factors of this phenomena, whether cognitive or subjective, remains poorly studied.

Furthermore, Self-Disorders are alterations of the first-person experience regarded as specific of the disease. The investigators plan to study in an exploratory way the phenomenological and subjective links between Praecox Feeling and Self Disorders determinants, while hypothesizing that the clinician's Praecox Feeling can be positively correlated to SDs, as our main objective.

Clinical Trial Description

Several authors suggest that the specific experience felt in clinical encounter, called Praecox Feeling, is directly linked to the psychopathology of Schizophrenia. However, subjective, cognitive or neurophysiologic aspects of this phenomena remains poorly studied.

Furthermore, Self-Disorders (SD) are alterations of the first-person experience and of sense of agency, regarded as specific of Schizophrenia. Unlike Praecox Feeling, clinical, cognitive and neuropsychological determinants of SD are increasingly studied.

The investigators plan to study in an exploratory way the links between Praecox Feeling and SDs determinants, while hypothesizing that the clinician's Praecox Feeling can be positively correlated to SDs, as our main objective.

As a secondary outcome, the investigators will control this correlation by a comparison between SDs evaluation and clinician subjectivity.

The present study also plan to evaluate the associations between Praecox Feeling and clinical features, low and high cognitive level with attentional and social cognition evaluations.

The first step of the research project is to implement this exploratory design in a transversal multicentric setting between centers with a limited number of participants and without follow-up. ;

Related Conditions & MeSH terms

• Schizophrenia

• NCT number: NCT05966610
• Study type: Observational
• Source: University Hospital, Toulouse
• Contact: Tudi GOZE, MD
• Phone: 5 61 77 23 60
• Email: goze.t@chu-toulouse.fr
• Status: Recruiting
• Start date: July 12, 2023
• Completion date: September 1, 2024