Schizophrenia Clinical Trial
— DYS FUTURS UHROfficial title:
Childhood Learning and Executive Function Disorders and Risk of Psychosis in the Adulthood
Verified date | August 2023 |
Source | Assistance Publique - Hôpitaux de Paris |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The primary objective of the study aims to study transition toward schizophrenia in patients with learning disorders, and to compare the risk between patients with specific learning disorders, and patients with complexed learning disorders (by two types: patients with other neuro-developmental disorders including executive function disorders, and patients with anxiety).
Status | Completed |
Enrollment | 20 |
Est. completion date | May 29, 2020 |
Est. primary completion date | May 29, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 15 Years to 30 Years |
Eligibility | Inclusion Criteria: - Patients born between 1990 and 2005, have been cared by Dr Schlumberger in 2014 in the center of language and learning disorders at Raymond Poincaré hospital; - With severe learning disorders: deficiency in school work, need at least one medical appointment and long-term rehabilitation in the center of language and learning disorders at Raymond Poincaré hospital; - Affiliated to a social protection schema; - Written informed consent signed. Exclusion Criteria: - Absence of learning disorder; - Intellectual deficiency; - Epilepsia; - Patients who will performed follow-up at Chartres city; - Patients under guardianship or curatorship; - Foreign patients under AME schema, a medical help from the state in France. |
Country | Name | City | State |
---|---|---|---|
France | Centre de référence des troubles du langage et des apprentissages, Hôpital Raymond Poincaré | Garches |
Lead Sponsor | Collaborator |
---|---|
Assistance Publique - Hôpitaux de Paris |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Semi-structured interview | Assessement with Comprehensive Assessment of At-Risk Mental States (CAARMS) during 6 to 90 minutes at the center of Raymond Poincaré hospital.
The unique collection during the interview, quotation of each patient will be given from the assessement. There will be 4 groups by the results: CAARMS negative subjects, vulnerable subjects, attenuated psychosis subjects and subjects with brief and limited intermittent psychotic syndrome. The further statistic comparison will be done between the 3 last groups classified with results of CAARMS. |
At baseline | |
Secondary | Autistic screening | Autism-spectrum quotient (AQ) auto-questionnaire will be used to evaluate difficulty in social interaction. | At baseline | |
Secondary | Anxiety measuring | An inventory for measuring clinical anxiety: Beck Anxiety Inventory | At baseline | |
Secondary | Social interaction difficulty evaluation | Liebowitz Social Anxiety Scale as questionnaire | At baseline |
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